1078719-77-3

Basic information

• Product Name: 1,1'-Biisoquinoline, 4,4'-bis[[6-[(4'-octyl[1,1'-biphenyl]-4-yl)oxy]hexyl]oxy]-
• Synonyms: 1,1'-Biisoquinoline, 4,4'-bis[[6-[(4'-octyl[1,1'-biphenyl]-4-yl)oxy]hexyl]oxy]-
• CAS NO: 1078719-77-3
• Molecular Formula: C₇₀H₈₄N₂O₄
• Molecular Weight: 1017.42696
• Mol File: 1078719-77-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,1'-Biisoquinoline, 4,4'-bis[[6-[(4'-octyl[1,1'-biphenyl]-4-yl)oxy]hexyl]oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-Biisoquinoline, 4,4'-bis[[6-[(4'-octyl[1,1'-biphenyl]-4-yl)oxy]hexyl]oxy]-(1078719-77-3)
• EPA Substance Registry System: 1,1'-Biisoquinoline, 4,4'-bis[[6-[(4'-octyl[1,1'-biphenyl]-4-yl)oxy]hexyl]oxy]-(1078719-77-3)

Safety Data

• Hazardous Substances Data: 1078719-77-3(Hazardous Substances Data)

Upstream product

• 1078719-73-9 1-chloro-4-({6-[(4'-octyl-1,1'-biphenyl-4-yl)oxy]hexyl}oxy)isoquinoline 

Relevant articles and documents

Convergent synthesis of 1,1′-biisoquinolines tethered to calamitic subunits

A convergent synthesis of a series of 4,4′-functionalized 1,1′-biisoquinolines via 1-chloro-4-hydroxyisoquinoline and substituted biphenyl- and phenylpyrimidine ethers as building blocks is described. The latter were prepared by Williamson etherification of the respective 4-hydroxybiphenyl and -phenylpyrimidine precursors with dibromoalkanes, allowing variation of the spacer lengths. 1-Chloro-4-hydroxyisoquinoline was obtained from N-phthalimidoglycine ethyl ester through a Gabriel-Colman reaction as a key step. Linkage of the building blocks by etherification in the presence of potassium carbonate gave the isoquinolines, which were submitted to a nickel(II) chloride mediated homocoupling to yield the ligand systems. Georg Thieme Verlag Stuttgart.