107879-44-7

Basic information

• Product Name: 1H-Benzimidazol-1-amine,2-chloro-(9CI)
• Synonyms: 1H-Benzimidazol-1-amine,2-chloro-(9CI);2-chlorobenzimidazol-1-amine
• CAS NO: 107879-44-7
• Molecular Formula: C7H6ClN3
• Molecular Weight: 167.59564
• Product Categories: BENZIMIDAZOLE
• Mol File: 107879-44-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Benzimidazol-1-amine,2-chloro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazol-1-amine,2-chloro-(9CI)(107879-44-7)
• EPA Substance Registry System: 1H-Benzimidazol-1-amine,2-chloro-(9CI)(107879-44-7)

Safety Data

• Hazardous Substances Data: 107879-44-7(Hazardous Substances Data)

Usage

Molecular Weight

161.6

Structure

A benzimidazole ring with an amine group (-NH2) and a chlorine atom (-Cl) attached

Appearance

Solid

Solubility

Soluble in common organic solvents such as DMSO, ethanol, and methanol

Melting Point

250-255°C

Boiling Point

Not readily available due to its stability as a solid

Polarity

Polar due to the presence of the amine group

Reactivity

Acts as a base in organic synthesis and as a ligand in coordination chemistry

Uses

Building block for the synthesis of various pharmaceuticals, development of new drugs and agrochemicals

Biological Activity

Potential for biological activity, but specific activity depends on the application and form used

Safety

May be harmful if ingested, inhaled, or absorbed through the skin; proper handling and safety precautions should be taken.

Upstream product

• 4857-06-1 2-chloro-1H-benzoimidazole 

Downstream Products

• 151693-49-1 1-amino-2-methylthiobenzimidazole 
• 151693-45-7 1-aminobenzimidazol-2-thione 

Relevant articles and documents

MUTUAL EFFECT OF THE N-AMINO GROUP AND THE HETERORING IN N-AMINOBENZAZOLES

The basicity constants, NH acidities, and anode oxidation potentials of N-amino derivatives of a number of heteroaromatic systems, viz., indole, benzimidazole, indazole, and 1,3-dimethylxanthine, were measured for the first time.The results obtained provide evidence for the inductive character of the interaction of the N-amino group and the benzazole ring vis-a-vis the almost complete absence of ? interaction between them; the heteroring has a very strong electron-acceptor effect on the properties of the amino group, while the amino group changes the properties of the heteroring to only a small extent.