107909-31-9Relevant academic research and scientific papers
The Addition of Alcohol to 1,2-Naphthoquinone Promoted by Metal Ions. A Facile Synthesis of 4-Alkoxy-1,2-naphthoquinones
Takuwa, Akio,Soga, Osamu,Iwamoto, Hidetoshi,Maruyama, Kazuhiro
, p. 2959 - 2961 (1986)
In the presence of some metal ions and sodium iodate, 1,2-naphthoquinone (1) readily racted with methanol to give 4-methoxy-1,2-naphthoquinone (2a).The activity of the metal ions increased in the following order: Co(II)Ni(II)Cu(II)La(III)Ce(III).The reaction was remarkably affected by the reaction temperature, reaction time, and molar ratio of the chelating agent.By the use of 1 equivalent of cerium salt to 1, the yield of 2a increased to 81percent at 20 deg C for 30 min.In higher alcohols, the addition reaction proceeded under similar conditions to give 4-alkoxy-1,2-naphthoquinones (2b-f) in 46-75percent yields.
