107910-75-8

Basic information

• Product Name: Ganciclovir sodium
• Synonyms: GANCICLOVIR SODIUM;2-amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6h-purin-6-one sodium salt;9-[[1-(Hydroxymethyl)-2-hydroxyethoxy]methyl]-2-amino-9H-purine-6(1H)-one/sodium,(1:1) salt;Ganciclovir monosodium salt;6H-Purin-6-one, 1,9-dihydro-2-amino-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, monosodium salt;6H-Purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, monosodium salt;Rs 21592 sodium;Unii-02L083W284
• CAS NO: 107910-75-8
• Molecular Formula: C₉H₁₂N₅O₄*Na
• Molecular Weight: 277.21
• EINECS: 1308068-626-2
• Mol File: 107910-75-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 675 °C at 760 mmHg
• Flash Point: 362 °C
• Appearance: /
• Density: 1.81g/cm3
• CAS DataBase Reference: Ganciclovir sodium(CAS DataBase Reference)
• NIST Chemistry Reference: Ganciclovir sodium(107910-75-8)
• EPA Substance Registry System: Ganciclovir sodium(107910-75-8)

Safety Data

• Hazardous Substances Data: 107910-75-8(Hazardous Substances Data)

Usage

Uses

Ganciclovir Sodium Salt is an inhibitor of the Herpesvirus family. It can be used in analytical study of establishment of a Raman database for non-invasive and rapid screening of liquid injectables.

Brand name

Cytovene (Roche).

InChI:InChI=1/C9H14N5O4.Na/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16;/h3,5,8,15-16H,1-2,4H2,(H3,10,12,13);/q-1;+1

Relevant articles and documents

Ganciclovir sodium synthesis process

The invention provides a ganciclovir sodium synthesis process which comprises the following steps: taking diacetylguanine as a raw material, mixing and heating diacetylguanine with p-toluene sulfonic acid and an N, N-dimethylformamide-methanol solution, then adding triacetylmethoxyglycerol for condensation, and adding methanol and an adsorbent in the condensation process so that the reaction is balanced and positively moved, the generation of triacetyl ganciclovir isomers is reduced, the product purity and yield are improved, and finally reaction is performed in a sodium hydroxide ethanol aqueous solution to obtain ganciclovir sodium. The ganciclovir sodium produced by the synthesis process is easy to operate, low in cost and easy to industrially produce.