1079274-53-5Relevant academic research and scientific papers
Anion receptors based on ureido-substituted thiacalix[4]arenes and calix[4]arenes
Kroupa, Jan,Stibor, Ivan,Pojarová, Michaela,Tkadlecová, Marcela,Lhoták, Pavel
, p. 10075 - 10079 (2008)
The regioselective nitration of 25,27-dipropoxythiacalix[4]arene was carried out as a key step in the synthesis of thiacalix[4]arene derivative bearing two arylureido functions on the upper rim. The preorganisation of ureido units using the thiacalix[4]arene/calix[4]arene moieties as a molecular scaffold gave novel anion receptors. These compounds, albeit based on hydrogen bonding interactions, show good complexation ability even in highly HB-competitive solvent, such as DMSO. Direct comparison of otherwise identical structures 6a and 7a revealed remarkable dominance of the thiacalix[4]arene derivative over its classical analogue in anion binding.
