1079304-57-6Relevant articles and documents
Tacrine based human cholinesterase inhibitors: Synthesis of peptidic-tethered derivatives and their effect on potency and selectivity
Butini, Stefania,Guarino, Egeria,Campiani, Giuseppe,Brindisi, Margherita,Coccone, Salvatore Sanna,Fiorini, Isabella,Novellino, Ettore,Belinskaya, Tatyana,Saxena, Ashima,Gemma, Sandra
, p. 5213 - 5216 (2008)
Tacrine based reversible inhibitors of cholinesterases (ChEIs) containing peptidic tethers were synthesized to interact with specific regions at the gorge level, and their potency was determined with human (h) acetylcholinesterase and butyrylcholinesteras