107932-09-2Relevant academic research and scientific papers
1,1-DICHLORO-2,2,2-TRIFLUOROETHYL ZINC AND LITHIUM COMPOUNDS IN ASYMMETRIC SYNTHESIS
Solladie-Cavallo, A.,Quazzotti, S.
, p. 221 - 228 (1990)
Addition of 1,1-dichloro-2,2,2-trifluoroethyl zinc chloride 2 complexed with optically pure ligands leads to zero percentage of asymmetric induction due to too large a distance between the chiral centers involved.However, addition of 2 and of the correspo
PbBr2/Al-Promoted Reductive Addition of 1,1,1-trichloro-2,2,2-trifluoroethane (Flon) to Aldehydes
Tanaka, Hideo,Yamashita, Shiro,Katayama, Yasumi,Torii, Sigeru
, p. 2043 - 2044 (2007/10/02)
Introduction of CF3CCl2 unit into aldehydes with CF3CCl3 has been perfomed successfully by the action of catalytic PbBr2 and Al foils in DMF.
EFFICIENT CARBON-CARBON BOND FORMATION WITH THERMALLY STABLE 1,1-DIHALO-2,2,2-TRIFLUOROETHYLZINC REAGENT
Fujita, Makoto,Morita, Tomoe,Hiyama, Tamejiro
, p. 2135 - 2138 (2007/10/02)
The zinc carbenoids CF3CX2ZnX, prepared from CF3CX3 and zinc powder in dimethylformamide, were found thermally stable to add to aldehyde carbonyls in excellent yields.
Fluorine-Containing Organozinc Reagents. Part I. A Simple Synthesis of 2,2-Dichloro-3,3,3-trifluoropropanol
Lang, Robert Werner
, p. 881 - 886 (2007/10/02)
The title compound 1, which can be regarded as synthetic equivalent of substituted 1,1,1-trifluoroacetone 2, is prepared by Zn-induced reductive addition of 1,1,1-trichloro-2,2,2-trifluoroethane (3) to formaldehyde (4).A brief survey of the scope of this C-C-bond formation leading to a variety of new CF3-containing synthetic building blocks is also given.
