1079355-18-2Relevant academic research and scientific papers
Synthesis of novel symmetrical bis-Schiff bases of 5,5′- methylenebis(2-aminothiazole)
Shockravi, Abbas,Olyaei, Abolfazl,Sadeghpour, Mahdieh
, p. 1473 - 1475 (2008)
(Chemical Equation Presented) Novel symmetrical bis-Schiff bases have been prepared cleanly and efficiently in the presence of formic acid catalyst in methanol from the reaction of symmetrical primary bis-amine of 5,5′-methylenebis(2-aminothiazole) (1) and a series of aromatic aldehyde derivatives under mild conditions. The advantages of this reaction are simplicity of the reaction procedure, simple work-up and pure products with high yields. The structures of all the new synthesized symmetrical bis-Schiff bases were confirmed by elemental analyses, IR, 1H-NMR, 13C-NMR and mass spectra.
Simple and efficient procedure for the synthesis of symmetrical bis-schiff bases of 5,5'-methylenebis(2-aminothiazole) under solvent-free conditions
Shockravi, Abbas,Sadeghpour, Mahdieh,Olyaei, Abolfazl
experimental part, p. 2531 - 2538 (2010/09/14)
A simple and efficient procedure for the synthesis of symmetrical bis-Schiff bases has been described that employs a condensation reaction of symmetrical primary bis-amine of 5,5'-methylenebis(2-aminothiazole) with a series of aromatic aldehyde derivatives under solvent-free conditions at elevated temperature. The advantages of these reactions are simplicity of the reaction procedure, short reaction times, simple workup, catalyst-free conditions, and pure products in good to excellent yields. Details of the reaction conditions are discussed. Taylor & Francis Group, LLC.
