1079649-94-7

Basic information

• Product Name: 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyriMidin-7-one
• Synonyms: 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyriMidin-7-one;2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d];7H-Pyrrolo[3,4-d]pyriMidin-7-one, 2,4-dichloro-5,6-dihydro-6-(1-Methylethyl)-;2,4-DICHLORO-6-ISOPROPYL-5H-PYRROLO[3,4-D]PYRIMIDIN-7(6H)-ONE
• CAS NO: 1079649-94-7
• Molecular Formula: C₉H₉Cl₂N₃O
• Molecular Weight: 246.09326
• EINECS: -0
• Mol File: 1079649-94-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 422.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.460±0.06 g/cm3(Predicted)
• PKA: -4.59±0.20(Predicted)
• CAS DataBase Reference: 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyriMidin-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyriMidin-7-one(1079649-94-7)
• EPA Substance Registry System: 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyriMidin-7-one(1079649-94-7)

Safety Data

• Hazardous Substances Data: 1079649-94-7(Hazardous Substances Data)

Usage

General Description

2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyrimidin-7-one is a synthetically derived chemical compound that belongs to the pyrimidine family. It is commonly used as a herbicide to control broadleaf weeds in various crops, including wheat, corn, and soybeans. This chemical works by disrupting the growth process of the weeds, ultimately leading to their death. While it is effective in controlling weeds, it is also important to handle and apply this chemical with care, as exposure to high doses can be harmful to human health. Therefore, proper safety precautions should be taken when using this chemical.

Upstream product

• 65-86-1 orotic acid 
• 4156-75-6 2,4-dihydroxyfuro[3,4-d]pyrimidin-7(5H)-one 
• 6341-93-1 orotic acid 
• 1079649-91-4 2,4-dihydroxy-6-isopropyl-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one 

Downstream Products

• 1079658-41-5 benzyl (2R)-1-[4-(4-acetylpiperazin-1-yl)-7-oxo-8-propan-2-yl-3,5,8-triazabicyclo[4.3.0]nona-1,3,5-trien-2-yl]pyrrolidine-2-carboxylate 
• 1079651-60-7 2-chloro-4-{[2-(4-chlorophenyl)-1,1-dimethylethyl]amino}-6-isopropyl-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one 
• 1079652-11-1 2-chloro-4-[2-(4-fluoro-phenyl)-1,1-dimethyl-ethylamino]-6-isopropyl-5,6-dihydro-pyrrolo[3,4-d]pyrimidin-7-one 
• 1079655-40-5 C₂₄H₂₉F₃N₆O₃ 
• 1079651-95-8 C₁₆H₁₆Cl₂N₄O 
• 1079653-78-3 2-(4-acetylpiperazin-1-yl)-6-isopropyl-4-{[(1R)-1-(4-methylphenyl)ethyl]amino}-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one 
• 1079653-34-1 C₂₄H₃₂N₆O₃ 

Relevant articles and documents

FUSED PYRIMIDINE COMPOUNDS AS KCC2

The invention concerns compounds of Formula (I): (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R7 and ring A have any of the meanings hereinbefore defined in the description; process for their preparation; pharmaceutical compositions containing them and their use in treating KCC2 mediated diseases.

PYRROLOPYRIMIDIN-7-ONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

Compounds of formula (I) or pharmaceutically acceptable salts thereof wherein R1, R2, R3, R4, and R5 and are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.