1079655-01-8

Basic information

• Product Name: 2-{4-[4-(benzhydryl-amino)-6-isopropyl-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl]-piperazin-1-yl}-N,N-dimethyl-acetamide
• CAS NO: 1079655-01-8
• Molecular Weight: 527.669
• Mol File: 1079655-01-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{4-[4-(benzhydryl-amino)-6-isopropyl-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl]-piperazin-1-yl}-N,N-dimethyl-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{4-[4-(benzhydryl-amino)-6-isopropyl-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl]-piperazin-1-yl}-N,N-dimethyl-acetamide(1079655-01-8)
• EPA Substance Registry System: 2-{4-[4-(benzhydryl-amino)-6-isopropyl-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl]-piperazin-1-yl}-N,N-dimethyl-acetamide(1079655-01-8)

Safety Data

• Hazardous Substances Data: 1079655-01-8(Hazardous Substances Data)

Upstream product

• 15783-48-9 2,4-dichlorofuro[3,4-d]pyrimidin-7(5H)-one 
• 1365640-53-4 C₂₇H₃₀N₆O₃ 
• 75-31-0 isopropylamine 
• 1079651-75-4 4-(benzhydryl-amino)-2-chloro-5H-furo[3,4-d]pyrimidin-7-one 
• 4156-75-6 2,4-dihydroxyfuro[3,4-d]pyrimidin-7(5H)-one 

Relevant articles and documents

Discovery of P2X3 selective antagonists for the treatment of chronic pain

Purinergic receptor P2X3 has been linked to analgesia in a number of pre-clinical models of pain, and is expressed in the human pain perception pathway. Only few P2X3-selective antagonists have been reported to date. This Letter describes the SAR and in vivo analgesic profile of a novel scaffold of selective P2X3 antagonists.