107972-85-0

Basic information

• Product Name: C₁₆H₂₁NO₃S
• Synonyms: C₁₆H₂₁NO₃S
• CAS NO: 107972-85-0
• Molecular Weight: 307.414
• Mol File: 107972-85-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₁NO₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₁NO₃S(107972-85-0)
• EPA Substance Registry System: C₁₆H₂₁NO₃S(107972-85-0)

Safety Data

• Hazardous Substances Data: 107972-85-0(Hazardous Substances Data)

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 86120-35-6 (3R,6S)-3,6-Dimethyl-1-oxo-3,6-dihydro-1H-1λ⁴-[1,2]thiazine-2-carboxylic acid benzyl ester 

Relevant articles and documents

DIASTEREOSELECTIVE SYNTHESIS OF HIGHLY FUNCTIONALIZED HOMOALLYLIC AMINE DERIVATIVES VIA DIELS-ALDER ADDUCTS OF N-SULFINYL DIENOPHILES

Novel methodology for the diastereoselective synthesis of some branched functionalized homoallylic amine derivatives is described.The protocol starts with a 3,6-dihydrothiazine-1-oxide, which is readily obtained in a totally stereospecific manner by the hetero-Diels-Alder cycloaddition of an N-sulfinyl dienophile and a 1,3-diene.Various Grignard reagents have been added to these adducts to afford sulfoxide derivatives which have been manipulated stereoselectively via -or -sigmatropic rearrangements into branched homoallylic amines potentially useful for further synthetic transformations.