1079906-81-2Relevant academic research and scientific papers
Synthesis and antifungal activity of (-)-(Z)-dysidazirine
Skepper, Colin K.,Dalisay, Doralyn S.,Molinski, Tadeusz F.
, p. 5269 - 5271 (2008)
(Chemical Equation Presented) A short, flexible synthesis of the marine natural product (2R)-(Z)-dysidazirine (-)-1 has been completed. (-)-1 shows significant antifungal activity across a panel of seven human pathogens, whereas the structural analogue (-)-2, featuring a terminal tert-butyl group, is essentially inactive.
