1079992-96-3

Usage

Uses

Used in Pharmaceutical Research and Development:
6-Fluoro-2-Methyl-3-Nitrobenzoic Acid is used as an intermediate in the production of various pharmaceuticals and agrochemicals. Its unique structure and functional groups make it a valuable building block for the synthesis of new compounds with potential therapeutic applications.
Used in Medicinal Chemistry:
6-Fluoro-2-Methyl-3-Nitrobenzoic Acid is used as a starting material for the development of new drugs in the field of medicinal chemistry. Its presence of a fluorine atom, which is known to enhance the lipophilicity and metabolic stability of compounds, makes it an attractive candidate for the design of novel therapeutic agents.
Used in Organic Synthesis:
6-Fluoro-2-Methyl-3-Nitrobenzoic Acid is used as a versatile building block in organic synthesis. Its functional groups can be selectively modified to generate a wide range of chemically diverse compounds, which can be further utilized in various applications, including the development of new materials, catalysts, and pharmaceuticals.

Upstream product

• 90259-27-1 2-fluoro-6-methylbenzoic acid 

Downstream Products

• 1403258-31-0 3-bromo-2-fluoro-6-methyl-5-nitrobenzoic acid 
• 1403258-37-6 3-bromo-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-5-[ethyl(oxan-4-yl)amino]-2-fluoro-6-methylbenzamide 
• 1403258-36-5 3-bromo-5-[ethyl(oxan-4-yl)amino]-2-fluoro-6-methylbenzoic acid 
• 1403258-35-4 methyl 3-bromo-5-[ethyl(oxan-4-yl)amino]-2-fluoro-6-methylbenzoate 
• 1403258-34-3 methyl 3-bromo-2-fluoro-6-methyl-5-[(oxan-4-yl)amino]benzoate 
• 1403258-33-2 methyl 3-amino-5-bromo-6-fluoro-2-methylbenzoate 
• 1403258-32-1 methyl 3-bromo-2-fluoro-6-methyl-5-nitrobenzoate 
• 1403256-01-8 N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-fluoro-4-methyl-4'-(morpholinomethyl)-[1,1'-biphenyl]-3-carboxamide 
• 1079992-97-4 methyl 6-fluoro-2-methyl-3-nitrobenzoate 

Relevant academic research and scientific papers

Preparation Method for Amide Compounds and Use Thereof in Medical Field

Provided are a preparation method for amide compounds and use thereof in medical field. Specifically, provided are small molecule amide compounds. Such compounds are inhibitors of enhancer homolog 2 (EZH2) of Zeste gene, and can be used for preventing and/or treating related diseases mediated by EZH2, including tumors, myeloproliferative diseases or autoimmune diseases.

NOVEL ISOINDOLINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF

Disclosed are a novel isoindoline derivative, a pharmaceutical composition and use thereof. The compound of formula I, or the pharmaceutically acceptable salt, solvate, polymorph, co-crystal, stereoisomer, isotopic compound, metabolite or prodrug thereof disclosed in the invention can regulate the generation and/or activity of PDE4 and/or TNF-α so as to effectively treat cancer and inflammatory diseases.

SUBSTITUTED N-(1H-INDAZOL-4-YL)IMIDAZO[1,2-a]PYRIDINE-3-CARBOXAMIDE COMPOUNDS AS TYPE III RECEPTOR TYROSINE KINASE INHIBITORS

Compounds of Formula I: and pharmaceutically acceptable salts thereof in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification, are inhibitors of cFMS and are useful in the treatment of fibrosis, bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases, pain and burns in a mammal

Aryl- or Heteroaryl-Substituted Benzene Compounds

The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

BICYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF

The present invention provides a compound represented by the formula wherein R1 is a hydrocarbon group optionally having substituent(s), amino optionally having substituent(s), hydroxy optionally having a substituent or a heterocyclic group optionally having substituent(s); R2 is a hydrogen atom or a hydrocarbon group optionally having substituent(s); Xa and Xb are each C, N, O or S; Xc and Xd are each C or N; m is 0-2; n is 1-3; ring A is a 5-membered ring optionally having substituent(s); ring B is a 6-membered ring optionally having substituent(s); and ring C is a 3- to 5-membered ring optionally having substituent(s), provided that when Xa, Xc and Xd are each C, then Xb is N or S, or a salt thereof, which is useful as an agent for the prophylaxis or treatment of a disease relating to an action of melatonin, and the like.

HETEROAROMATIC UREAS WHICH MODULATE THE FUNCTION OF THE VANILLOID-1 RECEPTOR (VR1)

Compounds of formula (I): are useful as therapeutic compounds, particularly in the treatment of pain and other conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VR1).