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Isopropyl acetate Manufacturer/High quality/Best price/In stock
Cas No: 108-21-4
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High quality Isopropyl Acetate supplier in China
Cas No: 108-21-4
No Data 1 Metric Ton 30 Metric Ton/Month Simagchem Corporation Contact Supplier
Isopropyl acetate
Cas No: 108-21-4
USD $ 12.0-12.0 / Kilogram 1 Kilogram 2000 Metric Ton/Year Jinan Finer Chemical Co., Ltd Contact Supplier
Isopropyl acetate 108-21-4
Cas No: 108-21-4
USD $ 1.0-3.0 / Kilogram 1 Kilogram 10 Kilogram/Day Hebei yanxi chemical co.,LTD. Contact Supplier
Isopropyl acetate 108-21-4
Cas No: 108-21-4
No Data 1 Kilogram 3000 Metric Ton/Year Hefei TNJ chemical industry co.,ltd Contact Supplier
Cas No: 108-21-4
No Data 1 Kilogram 20 Metric Ton/Month Henan Allgreen Chemical Co.,Ltd Contact Supplier
Iso-propyl acetate
Cas No: 108-21-4
USD $ 1.4-2.0 / Kilogram 1 Kilogram 100 Metric Ton/Day EAST CHEMSOURCES LIMITED Contact Supplier
Factory Supply Isopropyl acetate
Cas No: 108-21-4
No Data 1 1 Ality Chemical Corporation Contact Supplier
Amadis Chemical offer CAS#108-21-4;CAT#A801824
Cas No: 108-21-4
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
Isopropyl acetate
Cas No: 108-21-4
No Data No Data Metric Ton/Day ORCHID CHEMICAL SUPPLIES LTD Contact Supplier

108-21-4 Usage


Isopropyl acetate has an intense, fruity odor. On dilution, it has a sweet apple-like flavor. Synthesized by direct acetylation of isopropyl alcohol in the presence of various catalysts: concentrated H2S04, diethyl sulfate, chlorosulfonic acid, and boron trifluoride.

Chemical Properties

Isopropyl acetate has an intense, fruity odor. On dilution, it has a sweet apple-like flavor.

Chemical Properties

colourless liquid with a fruity odour

Physical properties

Clear, colorless liquid with an aromatic odor. Experimentally determined detection and recognition odor threshold concentrations were 2.1 mg/m3 (500 ppbv) and 3.8 mg/m3 (910 ppbv), respectively (Hellman and Small, 1974).


Reported found in pineapple, pear, cocoa, apple, banana, black currants, grapes, melons, strawberry, cheddar cheese, beer, white wine, red wine, cocoa, honey, soybean, yellow passion fruit, beans, plum brandy and nectarines


Isopropyl acetate is a solvent in chemical industry, especially for cellulose, plastics, waxes, resins, gums, paints, oil and fats. and also as flavoring agent. It is an active component of perfumes and printing inks. It is also employed as an extractant for the preparation of antibiotics, vitamins and hormones.


Solvent for cellulose derivatives, plastics, oils and fats; in perfumery.


Isopropyl acetate is used as a solvent fornitrocellulose, plastics, oils, and fats, and asa flavoring agent. Isopropyl Acetate is a widely used chemical solvent in organic and industrial syntheses. Also used in the dissolution of gallstones. Environmental contaminants; Food contaminants.


By direct acetylation of isopropyl alcohol in the presence of various catalysts; concentrated H2SO4, diethyl sulfate, chlorosulfonic acid and boron trifluoride.


ChEBI: A branched-chain saturated fatty acid anion that is the conjugate base of isovaleric acid; reported to improve ruminal fermentation and feed digestion in cattle.

Production Methods

Isopropyl acetate is prepared from propylene and anhydrous acetic acid in the presence of a catalyst . It may also be produced by reacting isopropyl alcohol with acetic acid in the presence of catalysts .

Aroma threshold values

Detection; 1.7 to 4.4 ppm

Taste threshold values

Taste characteristics at 60 ppm: ethereal, tutti-frutti, with a fruity apple and banana nuance

Synthesis Reference(s)

The Journal of Organic Chemistry, 39, p. 3728, 1974 DOI: 10.1021/jo00939a026

General Description

A clear colorless liquid. Flash point 40°F. Vapors are heavier than air. Contact with the material may irritate skin, eyes or mucous membranes. May be toxic by ingestion, inhalation and skin absorption. Used as a solvent.

Air & Water Reactions

Highly flammable. Less dense than water and slightly soluble in water.

Reactivity Profile

Isopropyl acetate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Isopropyl acetate can react vigorously with nitrates, strong oxidizers, strong alkalis and strong acids. Isopropyl acetate may also attack some forms of rubber, plastics and coatings. .


Flammable, dangerous fire risk.

Health Hazard

Vapors irritate eyes and respiratory tract; high concentrations can be anesthetic. Liquid irritates eyes but causes no serious injury; may cause dermatitis; no serious effects if swallowed.

Health Hazard

Isopropyl acetate is an irritant to the eyes,nose, and throat. The acute toxicity in laboratory animals was low. Exposure to highconcentrations in air or ingestion can produce narcotic effects. A 4-hour exposure to aconcentration of 32,000 ppm in air was fatalto rats (ACGIH 1986). The oral LD50 valuein rats is in the range 6000 mg/kg.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Chemical Reactivity

Reactivity with Water: No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.


Identified among 139 volatile compounds identified in cantaloupe (Cucumis melo var. reticulates cv. Sol Real) using an automated rapid headspace solid phase microextraction method (Beaulieu and Grimm, 2001).

Environmental fate

Chemical/Physical. Hydrolyzes in water forming isopropyl alcohol and acetic acid (Morrison and Boyd, 1971). The estimated hydrolysis half-life at 25 °C and pH 7 is 8.4 yr (Mabey and Mill, 1978). At an influent concentration of 1,000 mg/L, treatment with GAC resulted in an effluent concentration of 319 mg/L. The adsorbability of the carbon used was 137 mg/g carbon (Guisti et al., 1974).

Purification Methods

Wash the acetate with 50% aqueous K2CO3 (to remove acid), then with saturated aqueous CaCl2 (to remove any alcohol). Dry it with CaCl2 and fractionally distil it. [Beilstein 2 IV 141.]

108-21-4 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Alfa Aesar (L09337)  Isopropyl acetate, 99+%    108-21-4 250ml 205.0CNY Detail
Alfa Aesar (L09337)  Isopropyl acetate, 99+%    108-21-4 1000ml 427.0CNY Detail
Alfa Aesar (L09337)  Isopropyl acetate, 99+%    108-21-4 2500ml 786.0CNY Detail
Sigma-Aldrich (537462)  Isopropylacetate  ≥99.6% 108-21-4 537462-1L 1,178.19CNY Detail
Sigma-Aldrich (537462)  Isopropylacetate  ≥99.6% 108-21-4 537462-2.5L 2,027.61CNY Detail
Sigma-Aldrich (537462)  Isopropylacetate  ≥99.6% 108-21-4 537462-18L-CS 6,323.85CNY Detail
Sigma-Aldrich (45960)  Isopropylacetate  puriss. p.a., ≥99.5% (GC) 108-21-4 45960-250ML-F 437.58CNY Detail
USP (1350104)  Isopropylacetate  United States Pharmacopeia (USP) Reference Standard 108-21-4 1350104-3X1.2ML 4,662.45CNY Detail
Sigma-Aldrich (90871)  Isopropylacetate  analytical standard 108-21-4 90871-1ML-F 257.40CNY Detail
Sigma-Aldrich (90871)  Isopropylacetate  analytical standard 108-21-4 90871-5ML-F 851.76CNY Detail
Sigma-Aldrich (90871)  Isopropylacetate  analytical standard 108-21-4 90871-10ML-F 1,450.80CNY Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name Isopropyl acetate

1.2 Other means of identification

Product number -
Other names Acetic Acid Isopropyl Ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food additives -> Flavoring Agents
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

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