108031-79-4

Basic information

• Product Name: (-)-NOE'S REAGENT
• Synonyms: (-)-NOE'S REAGENT;(-)-NOE-LACTOL(R) DIMER;(2S,3AR,ES,7AR)-OCTAHYDRO-7,8,8-TRIMETHYL-4,7-METHANOBENZOFURAN-2-YL ETHER;(-)-MBF-OH DIMER;BIS[(2S,3AR,4S,7AR)-OCTAHYDRO-7,8,8-TRIMETHYL-4,7-METHANOBENZOFURAN-2-YL] ETHER;(-)-noe-lactol dimer;(-)-noe'S;BIS[(2S,3AR,4S,7AR)-OCTAHYDRO-7,8,8-TRIMETHYL-4,7-METHANOBENZOFURAN-2-YL] ETHER [FOR OPTICAL RESOLUTION] 98+%
• CAS NO: 108031-79-4
• Molecular Formula: C24H38O3
• Molecular Weight: 374.56
• Product Categories: for Resolution of Alcohols & Thiols;Optical Resolution;Synthetic Organic Chemistry
• Mol File: 108031-79-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 150-154 °C(lit.)
• Boiling Point: 435.9 °C at 760 mmHg
• Flash Point: 148.7 °C
• Appearance: /
• Density: 1.12 g/cm³
• Refractive Index: -202.5 ° (C=2, THF)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (-)-NOE'S REAGENT(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-NOE'S REAGENT(108031-79-4)
• EPA Substance Registry System: (-)-NOE'S REAGENT(108031-79-4)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 108031-79-4(Hazardous Substances Data)

Usage

General Description

(-)-NOE'S REAGENT, also known as (1S,2R)-(+)-norephedrine oxalate or 2-hydroxy-1,2-diphenylethanone oxime, is a chiral molecule commonly used in organic chemistry as a resolving agent for racemic mixtures. This reagent is a key component in the NOE's method, which involves the formation of diastereomeric crystalline salts with the racemic mixture, allowing for the separation of the enantiomers. By utilizing (-)-NOE'S REAGENT, chemists are able to isolate the individual enantiomers of a racemic mixture, providing the ability to study and utilize the distinct properties of each isomer in various applications.

Upstream product

• 108031-75-0 (1S,2R,4R,6R,7S)-1,10,10-Trimethyl-3-oxa-tricyclo[5.2.1.0^2,6]decan-4-ol 
• 81925-09-9 (1S,2R,4R,6R,7S)-1,10,10-Trimethyl-3-oxa-tricyclo[5.2.1.0^2,6]decan-4-ol 
• 81969-33-7 (3aR-(3aα,4β,7β,7aα))-3a,4,5,6,7,7a-Hexahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2(3H)-on 
• 108031-76-1 <2R-(2α,3aα,4β,7β,7aα)>-Octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-ol 

Relevant articles and documents

Stereoelektronische Effekte und chirale Erkennung: Ein natuerliches Verwandtschaftssystem chiraler Verbindungen basierend auf Selektivitaeten bei der Acetalbildung

-