108047-39-8

Basic information

• Product Name: 2-(AMINOMETHYL)-4-CHLOROANILINE
• Synonyms: 2-AMINOMETHYL-4-CHLORO-PHENYLAMINE;2-(AMINOMETHYL)-4-CHLOROANILINE;RARECHEM AL BW 0318;Benzenemethanamine, 2-amino-5-chloro-;2-Amino-5-chlorobenzylamine
• CAS NO: 108047-39-8
• Molecular Formula: C₇H₉ClN₂
• Molecular Weight: 156.61
• Product Categories: pharmacetical
• Mol File: 108047-39-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 298.9°C at 760 mmHg
• Flash Point: 134.5°C
• Appearance: /
• Density: 1.266g/cm³
• Vapor Pressure: 0.00124mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 9.30±0.10(Predicted)
• CAS DataBase Reference: 2-(AMINOMETHYL)-4-CHLOROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(AMINOMETHYL)-4-CHLOROANILINE(108047-39-8)
• EPA Substance Registry System: 2-(AMINOMETHYL)-4-CHLOROANILINE(108047-39-8)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39
• Hazardous Substances Data: 108047-39-8(Hazardous Substances Data)

Usage

General Description

2-(aminomethyl)-4-chloroaniline is a chemical compound with the molecular formula C7H8ClN. It is an organic compound that is classified as an aniline, which is a type of aromatic amine. This chemical is a derivative of aniline with a chlorine atom attached to the fourth carbon and an amino methyl group attached to the second carbon in the benzene ring. It is commonly used in the synthesis of various chemical compounds and can be found in some industrial processes. It is important to handle this chemical with caution, as it may have some harmful effects on health and the environment.

InChI:InChI=1/C7H9ClN2/c8-6-1-2-7(10)5(3-6)4-9/h1-3H,4,9-10H2

Upstream product

• 5202-85-7 2-Amino-5-chlorobenzamide 
• 5922-60-1 2-amino-5-chlorobenzonitrile 
• 67567-44-6 (5-chloro-2-nitrophenyl)-methylamine 

Downstream Products

• 58058-53-0 6-chloro-2-phenylquinazoline 
• 1353000-33-5 6-chloro-2-(4-methoxyphenyl)quinazoline 
• 1226808-00-9 7-chloro-2-oxo-1,2,3,5-tetrahydrobenzo[1,4]diazepine-4-carboxylic acid tert-butyl ester 
• 1353000-34-6 6-chloro-2-(4-chlorophenyl)quinazoline 
• 258850-08-7 7-chloro-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one 

Relevant articles and documents

New V1a receptor antagonist. Part 1. Synthesis and SAR development of urea derivatives

Solid preclinical evidence links vasopressin to social behavior in animals, so, extensive work has been initiated to find new vasopressin V1a receptor antagonists which can improve deteriorated social behavior in humans and can treat the core symptoms of

"Methylene Bridge" to 5-HT3 Receptor Antagonists: Conformationally Constrained Phenylguanidines

Arylguanidines, depending upon their aromatic substitution pattern, display varying actions at 5-HT3 receptors (e.g., partial agonist, agonist, superagonist). Here, we demonstrate that conformational constraint of these agents as dihydroquinazo

Preparation of triazolobenzodiazepine derivatives as Vasopressin V1a antagonists

This Letter describes the synthesis of a number of fused tricyclic and bicyclic triazolobenzodiazepines for the Vasopressin V1a antagonist programme.