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108050-28-8

Cytochalasin N, a naturally occurring fungal metabolite, is a member of the cytochalasins family. It is known for its ability to inhibit actin polymerization in eukaryotic cells by binding to the barbed end of actin filaments, preventing the addition of monomers and leading to depolymerization of actin fibers. This disruption of the actin cytoskeleton can have various biological effects, such as impairing cell motility, cytokinesis, and cellular trafficking. Due to its potential to modulate cellular processes, cytochalasin N has been extensively studied and is of interest for its potential therapeutic applications in treating various diseases and conditions.

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  • 108050-28-8 Structure

  • Basic information

    1. Product Name: CYTOCHALASINN
    2. Synonyms: CYTOCHALASINN;(7S,13E,16S,18R,19E,21R)-21-Acetyloxy-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-5,13,19-trien-1-one
    3. CAS NO:108050-28-8
    4. Molecular Formula: C30H39NO5
    5. Molecular Weight: 493.6344
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 108050-28-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 678.6°Cat760mmHg
    3. Flash Point: 364.2°C
    4. Appearance: /
    5. Density: 1.2g/cm3
    6. Vapor Pressure: 2.42E-19mmHg at 25°C
    7. Refractive Index: 1.595
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: CYTOCHALASINN(CAS DataBase Reference)
    11. NIST Chemistry Reference: CYTOCHALASINN(108050-28-8)
    12. EPA Substance Registry System: CYTOCHALASINN(108050-28-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 108050-28-8(Hazardous Substances Data)

108050-28-8 Usage

Uses

Used in Research Applications:
Cytochalasin N is used as a research tool for studying the role of the actin cytoskeleton in various cellular processes. Its ability to disrupt actin dynamics makes it a valuable agent for investigating cell motility, cytokinesis, and cellular trafficking.
Used in Drug Development:
Cytochalasin N is used as a lead compound in the development of new drugs targeting the actin cytoskeleton. Its potential therapeutic applications are being explored for the treatment of various diseases and conditions that involve dysregulation of actin dynamics.
Used in Cancer Therapy:
Cytochalasin N is being investigated for its potential use in cancer therapy. Its ability to disrupt the actin cytoskeleton can lead to the inhibition of cancer cell migration, invasion, and metastasis, making it a promising candidate for the development of anti-cancer agents.
Used in Neurodegenerative Disease Research:
Cytochalasin N is used in research to understand the role of the actin cytoskeleton in neurodegenerative diseases. Its effects on cellular processes can provide insights into the mechanisms underlying these diseases and aid in the development of potential therapeutic interventions.
Used in Wound Healing and Tissue Repair:
Cytochalasin N is used in research to study the role of the actin cytoskeleton in wound healing and tissue repair. Its ability to modulate cellular processes involved in these processes can help in the development of new treatments for promoting wound healing and tissue regeneration.
Used in Cell Biology Education:
Cytochalasin N is used as an educational tool in cell biology to demonstrate the importance of the actin cytoskeleton in various cellular functions. It helps students understand the role of actin dynamics in cell motility, cytokinesis, and cellular trafficking.

Check Digit Verification of cas no

The CAS Registry Mumber 108050-28-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,0,5 and 0 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 108050-28:
(8*1)+(7*0)+(6*8)+(5*0)+(4*5)+(3*0)+(2*2)+(1*8)=88
88 % 10 = 8
So 108050-28-8 is a valid CAS Registry Number.
InChI:InChI=1/C30H39NO5/c1-18-10-9-13-23-27(33)20(3)19(2)26-24(16-22-11-7-6-8-12-22)31-28(34)30(23,26)25(36-21(4)32)14-15-29(5,35)17-18/h6-9,11-15,18,23-27,33,35H,10,16-17H2,1-5H3,(H,31,34)/b13-9+,15-14+

108050-28-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Cytochalasin Npho

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:108050-28-8 SDS

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