1080563-91-2Relevant academic research and scientific papers
Palladium-catalyzed sequential carbon-carbon bond cleavage/formation producing arylated benzolactones
Matsuda, Takanori,Shigeno, Masanori,Murakami, Masahiro
, p. 5219 - 5221 (2008)
(Chemical Equation Presented) 3-(2-Hydroxyphenyl)cyclobutanones react with aryl bromides in the presence of palladium catalysts to afford 4-arylmethyl-3,4-dihydrocoumarins in high yields through a sequence involving carbon-carbon bond cleavage and formation. In the case of the reaction with 2-(2-hydroxyphenyl)cyclobutanones, five- or seven-membered lactones were produced depending on the presence of an additional substituent at the 2-position.
