108060-52-2Relevant academic research and scientific papers
Novel imidazo[1,5-a]pyridines, useful as cardiovascular and CNS agents
-
, (2008/06/13)
This invention relates to novel substituted imidazo-[1,5-a]pyridines, most especially novel 8-phenylimidazo-[1,5-a]pyridines. It also relates to novel intermediates and to a novel process for the preparation of certain of these compounds. The compounds of
Synthesis and antiarrhythmic activity of novel 3-alkyl-1-[ω-[4-[(alkylsulfonyl)amino]phenyl]-ω-hydroxyalkyl]-1H-im dazolium salts and related compounds
Lis,Davey,Morgan Jr.,Lumma Jr.,Wohl,Jain,Wan,Argentieri,Sullivan,Cantor
, p. 2303 - 2309 (2007/10/02)
Novel analogues of the class III antiarrhythmic agent 1-[2-hydroxy-2-[4-[(methylsulfonyl)amino]phenyl]ethyl]-3-methyl-1H-im dazolium chloride, 1 (CK-1649), were prepared and investigated for their class III electrophysiological activity on isolated canine
Cardiotonic agents. 1. Novel 8-aryl-substituted imidazo[1,2-a]- and -[1,5-a]pyridines and imidazo[1,5-a]pyridinones as potential positive inotropic agents
Davey,Erhardt,Lumma Jr.,Wiggins,Sullivan,Pang,Cantor
, p. 1337 - 1342 (2007/10/02)
Several 8-arylimidazo[1,2-a]pyridines, 8-arylimidazo[1,5-a]pyridines, and 8-arylimidazo[1,5-a]pyridinones were prepared and tested in vitro for potential cardiac inotropic and electrophysiological activity. Selected analogues were further tested in vivo i
