108122-25-4 Usage
General Description
1-(6-ethoxypyridin-2-yl)piperazine is a chemical compound that has a piperazine ring with a pyridine group and an ethoxy side chain. It is often used as a building block in the synthesis of pharmaceuticals and other organic compounds. 1-(6-ETHOXYPYRIDIN-2-YL)PIPERAZINE has applications in medicinal chemistry, particularly in the development of drugs that target neurological and psychiatric disorders. Its structure and properties make it a valuable intermediate for the production of various bioactive molecules. Additionally, 1-(6-ethoxypyridin-2-yl)piperazine may also have potential applications as a research tool in chemical biology and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 108122-25-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,1,2 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 108122-25:
(8*1)+(7*0)+(6*8)+(5*1)+(4*2)+(3*2)+(2*2)+(1*5)=84
84 % 10 = 4
So 108122-25-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H17N3O/c1-2-15-11-5-3-4-10(13-11)14-8-6-12-7-9-14/h3-5,12H,2,6-9H2,1H3
108122-25-4Relevant articles and documents
6-Alkoxy-N,N-disubstituted-2-pyridinamines as Anticonvulsant Agents
Pavia, Michael R.,Taylor, Charles P.,Hershenson, Fred M.,Lobbestael, Sandra J.
, p. 1210 - 1214 (2007/10/02)
The anticonvulsant effect of a series of 6-alkoxy-N,N-disubstituted-2-pyridinamines is described. An investigation was carried out to optimize the activity/side-effect ratio in this series of compounds. The most desirable profile was seen with 1-piperazine, 6, and this compound was selected for a more complete pharmacological evaluation. Overall, 6 has a pharmacological profile that is very similar to that of diphenylhydantoin (phenytoin). While nearly equipotent to phenytoin, animal studies suggest a fairly short duration of action. In addition, 6 exhibited some troublesome side effects including central nervous system depression and hypothermia.
