108122-83-4

Basic information

• Product Name: 1-(6-amino-[1,1'-biphenyl]-3-yl)ethanone
• Synonyms: 1-(6-amino-[1,1'-biphenyl]-3-yl)ethanone
• CAS NO: 108122-83-4
• Molecular Weight: 211.263
• Mol File: 108122-83-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(6-amino-[1,1'-biphenyl]-3-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-amino-[1,1'-biphenyl]-3-yl)ethanone(108122-83-4)
• EPA Substance Registry System: 1-(6-amino-[1,1'-biphenyl]-3-yl)ethanone(108122-83-4)

Safety Data

• Hazardous Substances Data: 108122-83-4(Hazardous Substances Data)

Upstream product

• 56759-32-1 1-(4-amino-3-bromophenyl)-ethanone 
• 98-80-6 phenylboronic acid 

Downstream Products

• 4630-20-0 3-Methyl-9H-carbazole 

Relevant articles and documents

Palladium-Catalyzed Intramolecular C–H Amination in Water

Palladium(II) catalysis was found to be effective for intramolecular C–H amination in water. With 2-azidobiphenyls as substrates, the reaction efficiently provided various carbazoles with N2as the sole byproduct. The reaction showed high functional-group tolerance and could be used in the synthesis of several natural carbazole alkaloids. The catalytic process was promoted by water, and the reaction was inefficient in the organic solvents that were investigated.

Visible-light-promoted intramolecular C-H amination in aqueous solution: Synthesis of carbazoles

An effective and operationally simple protocol is reported for the synthesis of versatile carbazoles. With water as a co-solvent, visible-light rather than various metals is used to facilitate the conversion of readily available 2-azidobiphenyls under mild conditions. Various functionalized bioactive natural alkaloids, such as glycoborine, clausine C, clausine L, clausine H and clauszoline K, were synthesized efficiently with nitrogen as a sole byproduct. The reaction could be performed in water, acidic or alkaline buffer solutions, showing its potential for applications in biochemistry.