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  • 1081314-82-0 Structure
  • Basic information

    1. Product Name: C16H21NO6
    2. Synonyms:
    3. CAS NO:1081314-82-0
    4. Molecular Formula:
    5. Molecular Weight: 323.346
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1081314-82-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C16H21NO6(CAS DataBase Reference)
    10. NIST Chemistry Reference: C16H21NO6(1081314-82-0)
    11. EPA Substance Registry System: C16H21NO6(1081314-82-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1081314-82-0(Hazardous Substances Data)

1081314-82-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1081314-82-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,1,3,1 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1081314-82:
(9*1)+(8*0)+(7*8)+(6*1)+(5*3)+(4*1)+(3*4)+(2*8)+(1*2)=120
120 % 10 = 0
So 1081314-82-0 is a valid CAS Registry Number.

1081314-82-0Upstream product

1081314-82-0Downstream Products

1081314-82-0Relevant articles and documents

Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide and its biological evaluation

Uto, Yoshikazu,Ogata, Tsuneaki,Kiyotsuka, Yohei,Miyazawa, Yuriko,Ueno, Yuko,Kurata, Hitoshi,Deguchi, Tsuneo,Yamada, Makiko,Watanabe, Nobuaki,Takagi, Toshiyuki,Wakimoto, Satoko,Okuyama, Ryo,Konishi, Masahiro,Kurikawa, Nobuya,Kono, Keita,Osumi, Jun

scheme or table, p. 4159 - 4166 (2010/04/24)

The continuing investigation of SAR studies of 3-(2-hydroxyethoxy)-N-(5-benzylthiazol-2-yl)-benzamides as stearoyl-CoA desaturase-1 (SCD-1) inhibitors is reported. Our prior hit-to-lead effort resulted in the identification of 1a as a potent and orally efficacious SCD-1 inhibitor. Further optimization of the structural motif resulted in the identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide (37c) with sub nano molar IC50 in both murine and human SCD-1 inhibitory assays. This compound demonstrated a dose-dependent decrease in the plasma desaturation index in C57BL/6J mice on a non-fat diet after 7 days of oral administration.

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