108153-74-8

Basic information

• Product Name: Secretin (human)
• Synonyms: SECRETIN, HUMAN;HSDGTFTSELSRLREGARLQRLLQGLV-NH3;HSDGTFTSELSRLREGARLQRLLQGLV-NH2;HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2;HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2 HUMAN;H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2;H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH3;SECRETINHCL
• CAS NO: 108153-74-8
• Molecular Formula: C130H220N44O40
• Molecular Weight: 3039.41
• EINECS: 241-105-3
• Product Categories: Peptide;Gastrointestinal Peptides;Hormones;Other Protein/Peptide Hormones;SecretinPeptides for Cell Biology;Secretins;VIP and PACAP receptor;EndocrinologyandHormones
• Mol File: 108153-74-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /powder
• Density: 1.49±0.1 g/cm3(Predicted)
• Storage Temp.: −20°C
• CAS DataBase Reference: Secretin (human)(CAS DataBase Reference)
• NIST Chemistry Reference: Secretin (human)(108153-74-8)
• EPA Substance Registry System: Secretin (human)(108153-74-8)

Safety Data

• WGK Germany: 3
• RTECS: VS4030000
• Hazardous Substances Data: 108153-74-8(Hazardous Substances Data)

Usage

Uses

Secretin human has been used:in the radioimmunoassay with oxyntomodulinto test its effect on the enlargement and swelling of human endoderm stem cells (hEnSCs) derived cystto stimulate human induced pluripotent stem cells (iPSC)-derived biliary cells in cyclic adenosine monophosphate (cAMP) assays to test its effect on cAMP production

General Description

Secretin is a gastrointestinal hormone and a neuropeptide. It is synthesized from a precursor protein and shares sequence homology with other secretin family proteins like glucagon and vasoactive intestinal peptide (VIP).

Biochem/physiol Actions

Secretin regulates the secretion of gastric acid and pancreatic bicarbonates. It serves as an antidiuretic hormone in the neurohypophysial-renal axis and participates in osmoregulation. Secretin mediates its function through the G-protein coupled secretin receptors. It regulates the pH of the duodenal by modulating gastric acid secretion.