108160-41-4Relevant academic research and scientific papers
Synthesis of Substituted 2-(2-Oxobenzopyran-3-yl)indoles
Sinnur, K. H.,Siddappa, S.,Hiremath, Shivayogi P.,Purohit, Muralidhar G.
, p. 894 - 896 (2007/10/02)
3-Acetylbenzopyran-2-one (1) reacts with bromine in CHCl3 to give 3-(ω-bromoacetyl)benzopyran-2-one (2) which on reaction with substituted anilines (3) gives the corresponding ω-anilino-3-acetylbenzopyran-2-ones (4).The latter compounds (4) under Bischler indole synthesis reaction conditions yield the respective 2-(2-oxo-benzopyran-3-yl)indoles (6).The biheterocycles thus obtained have been subjected to electrophilic substitution reactions such as formylation and bromination.The position of the substitution has been established on the basis of spectral data.
