108160-43-6

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 3-[[(4-chlorophenyl)amino]acetyl]-
• CAS NO: 108160-43-6
• Molecular Formula: C17H12ClNO3
• Molecular Weight: 313.74
• Mol File: 108160-43-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 3-[[(4-chlorophenyl)amino]acetyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 3-[[(4-chlorophenyl)amino]acetyl]-(108160-43-6)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 3-[[(4-chlorophenyl)amino]acetyl]-(108160-43-6)

Safety Data

• Hazardous Substances Data: 108160-43-6(Hazardous Substances Data)

Upstream product

• 29310-88-1 3-bromoacetylcoumarin 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 164590-67-4 1-(4-chlorophenyl)-2-mercapto-4-(coumarin-3-yl)imidazole 
• 1296213-61-0 3-(1-(4-chlorophenyl)-2-((Z)-styrylsulfonyl)-1H-imidazol-4-yl)-2H-chromen-2-one 

Relevant articles and documents

Efficient, stereoselective approach to the synthesis of 3-(1-Phenyl-2-(Z-styrylsulfonyl)-1H-imidazol-4-yl)-2H-chromen-2-ones

Reaction of phenyl acetylene with 3-(1-aryl-2-mercapto-4-imidazolyl)-2H-1- benzopyran-2-ones (4) in the presence of sodium hydroxide in absolute ethanol led to the formation of 3-(1-phenyl-2-(Z-styrylthio)-1H-imidazol-4-yl)-2H- chromen-2-ones (6) in excel

Synthesis of Substituted 2-(2-Oxobenzopyran-3-yl)indoles

3-Acetylbenzopyran-2-one (1) reacts with bromine in CHCl3 to give 3-(ω-bromoacetyl)benzopyran-2-one (2) which on reaction with substituted anilines (3) gives the corresponding ω-anilino-3-acetylbenzopyran-2-ones (4).The latter compounds (4) under Bischler indole synthesis reaction conditions yield the respective 2-(2-oxo-benzopyran-3-yl)indoles (6).The biheterocycles thus obtained have been subjected to electrophilic substitution reactions such as formylation and bromination.The position of the substitution has been established on the basis of spectral data.