1082-23-1

Basic information

• Product Name: 1-(2,3,4-trimethoxyphenyl)propan-2-amine
• Synonyms: 1-(2,3,4-trimethoxyphenyl)propan-2-amine;2,3,4-Trimethoxyamphetamine;2,3,4-Trimethoxy-α-methylbenzeneethanamine;TMA-3;α-Methyl-2,3,4-trimethoxybenzeneethaneamine;α-Methyl-2,3,4-trimethoxyphenethylamine
• CAS NO: 1082-23-1
• Molecular Formula: C₁₂H₁₉NO₃
• Molecular Weight: 225.2842
• Mol File: 1082-23-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 311.8°Cat760mmHg
• Flash Point: 140.5°C
• Appearance: /
• Density: 1.048g/cm³
• Vapor Pressure: 0.000549mmHg at 25°C
• Refractive Index: 1.507
• CAS DataBase Reference: 1-(2,3,4-trimethoxyphenyl)propan-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,3,4-trimethoxyphenyl)propan-2-amine(1082-23-1)
• EPA Substance Registry System: 1-(2,3,4-trimethoxyphenyl)propan-2-amine(1082-23-1)

Safety Data

• Hazardous Substances Data: 1082-23-1(Hazardous Substances Data)

Usage

General Description

1-(2,3,4-trimethoxyphenyl)propan-2-amine is a chemical compound with the molecular formula C11H17NO3. It is also known by the names TMA-6 and 2,4,5-trimethoxyamphetamine. 1-(2,3,4-trimethoxyphenyl)propan-2-amine is a member of the phenethylamine and amphetamine chemical classes, and it is structurally similar to the psychedelic drug mescaline. 1-(2,3,4-trimethoxyphenyl)propan-2-amine has been studied for its potential psychoactive effects, and it is believed to act as a serotonin receptor agonist. Like other psychedelic substances, it has the potential to alter perception, mood, and cognition, and it is classified as a schedule I controlled substance in the United States. More research is needed to fully understand the effects and safety profile of this compound.

InChI:InChI=1/C12H19NO3/c1-8(13)7-9-5-6-10(14-2)12(16-4)11(9)15-3/h5-6,8H,7,13H2,1-4H3

Upstream product

• 5556-77-4 1-(2,3,4-Trimethoxyphenyl)-2-nitropropene 
• 134040-33-8 1-(2,3,4-trimethoxyphenyl)-2-nitropropene 
• 2103-57-3 2,3,4-trimethoxybenzaldehyde 

Relevant articles and documents

Discrimination and identification of the six aromatic positional isomers of trimethoxyamphetamine (TMA) by gas chromatography-mass spectrometry (GC-MS)

A reliable and accurate GC-MS method was developed that allows both mass spectrometric and chromatographic discrimination of the six aromatic positional isomers of trimethoxyamphetamine (TMA). Regardless of the trifluoroacetyl (TFA) derivatization, chromatographic separation of all the investigated isomers was achieved by using DB-5ms capillary columns (30 m x 0.32 mm i.d.), with run times less than 15 min. However, the mass spectra of the nonderivatized TMAs, except 2,4,6-trimethoxyamphetmine (TMA-6), showed insufficient difference for unambiguous discrimination. On the other hand, the mass spectra of the TFA derivatives of the six isomers exhibited fragments with significant intensity differences, which allowed the unequivocal identification of all the aromatic positional isomers investigated in the present study. This GC-MS technique in combination with TFA derivatization, therefore, is a powerful method to discriminate these isomers, especially useful to distinguish the currently controlled 3,4,5-trimethoxyamphetmine (TMA-1) and 2,4,5-trimethoxyamphetmine (TMA-2) from other uncontrolled TMAs. Copyright

The six trimethoxyphenylisopropylamines (trimethoxyamphetamines).

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