1082065-99-3

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
1-CyclopropylMethyl-1H-pyrazole-4-carbaldehyde is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals for its ability to contribute to the development of new drugs and pesticides.
Used in Organic Chemistry:
1-CyclopropylMethyl-1H-pyrazole-4-carbaldehyde is used as a versatile reagent in organic chemistry for the synthesis of complex molecules, highlighting its utility in creating intricate chemical structures for research and commercial applications.
Used in Drug Discovery and Development:
1-CyclopropylMethyl-1H-pyrazole-4-carbaldehyde is used as a building block in the synthesis of heterocyclic compounds, which are often found in biologically active molecules, thus playing a significant role in the advancement of new therapeutic agents.

Upstream product

• 7051-34-5 cyclopropylcarbinyl bromide 
• 35344-95-7 1H-pyrazole-4-carbaldehyde 

Relevant academic research and scientific papers

HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS

Disclosed are heterocyclic heteroaromatic macrocyclic ether compounds, pharmaceutically acceptable salts of the compounds and pharmaceutical compositions thereof. The disclosure further relates to methods of treating or preventing cancer using the heterocyclic heteroaromatic macrocyclic ether compounds, pharmaceutically acceptable salts of the compounds and pharmaceutical compositions thereof.

SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS

The application relates to substituted hydantoinamides of formula (I) as ADAMTS7 antagonists, to processes for their preparation, their use alone or in combination for the treatment or prophylaxis of diseases, in particular of cardiovascular diseases, including atherosclerosis, coronary artery disease (CAD), peripheral vascular disease (PAD), arterial occlusive disease or restenosis after angioplasty. R1 is hydrogen, alkyl, cycloalkyl, heterocycloalkyl, 5- to 6-membered heteroaryl or phenyl; R2 is hydrogen or alkyl; A is 5-membered heteroaryl; Z is 6- to 10-membered aryl or 5- to 10-membered heteroaryl; all groups being optionally substituted.

2-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-3-PHENYL PYRAZINES AND PYRIDINES AND 3-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-2-PHENYL PYRIDINES AS 5-HT7 RECEPTOR ANTAGONISTS

The present invention provides selective 5-HT7 receptor antagonist compounds of Formula I and their use in the treatment of migraine, persistent pain, and anxiety: where A and B are each independently C(H)= or N=, provided that at least one of A and B is -N=, n is 1-3, m is 0-3, and R14 are as defined herein.