1082065-99-3

Basic information

• Product Name: 1-CyclopropylMethyl-1H-pyrazole-4-carbaldehyde
• Synonyms: 1-CyclopropylMethyl-1H-pyrazole-4-carbaldehyde;1-(Cyclopropylmethyl)-1H-pyrazole-4-carboxaldehyde
• CAS NO: 1082065-99-3
• Molecular Formula: C8H10N2O
• Molecular Weight: 150.1778
• Mol File: 1082065-99-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-CyclopropylMethyl-1H-pyrazole-4-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CyclopropylMethyl-1H-pyrazole-4-carbaldehyde(1082065-99-3)
• EPA Substance Registry System: 1-CyclopropylMethyl-1H-pyrazole-4-carbaldehyde(1082065-99-3)

Safety Data

• Hazardous Substances Data: 1082065-99-3(Hazardous Substances Data)

Usage

General Description

1-CyclopropylMethyl-1H-pyrazole-4-carbaldehyde is a chemical compound with the molecular formula C10H10N2O. It is a pyrazole derivative that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 1-CyclopropylMethyl-1H-pyrazole-4-carbaldehyde is synthesized by the reaction of cyclopropylmethylamine and 4-formylpyrazole in the presence of an acid catalyst. It is commonly used as a building block in the synthesis of various heterocyclic compounds and has shown potential pharmacological activity, making it a valuable compound in drug discovery and development. Additionally, it has applications in the field of organic chemistry as a versatile reagent for the synthesis of complex molecules.

Upstream product

• 7051-34-5 cyclopropylcarbinyl bromide 
• 35344-95-7 1H-pyrazole-4-carbaldehyde 

Relevant articles and documents

SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS

The application relates to substituted hydantoinamides of formula (I) as ADAMTS7 antagonists, to processes for their preparation, their use alone or in combination for the treatment or prophylaxis of diseases, in particular of cardiovascular diseases, including atherosclerosis, coronary artery disease (CAD), peripheral vascular disease (PAD), arterial occlusive disease or restenosis after angioplasty. R1 is hydrogen, alkyl, cycloalkyl, heterocycloalkyl, 5- to 6-membered heteroaryl or phenyl; R2 is hydrogen or alkyl; A is 5-membered heteroaryl; Z is 6- to 10-membered aryl or 5- to 10-membered heteroaryl; all groups being optionally substituted.

2-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-3-PHENYL PYRAZINES AND PYRIDINES AND 3-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-2-PHENYL PYRIDINES AS 5-HT7 RECEPTOR ANTAGONISTS

The present invention provides selective 5-HT7 receptor antagonist compounds of Formula I and their use in the treatment of migraine, persistent pain, and anxiety: where A and B are each independently C(H)= or N=, provided that at least one of A and B is -N=, n is 1-3, m is 0-3, and R14 are as defined herein.