1082502-70-2Relevant academic research and scientific papers
A DFT study of 1,3-dipolar cycloadditions of cyclic nitrones to unsaturated lactones. Part II
Stecko, Sebastian,Pasniczek, Konrad,Michel, Carine,Milet, Anne,Perez, Serge,Chmielewski, Marek
experimental part, p. 2140 - 2148 (2009/04/04)
The 1,3-dipolar cycloadditions of cyclic nitrones to five-membered unsaturated lactones are studied. Special attention was focused on a single and double asymmetric induction when one or both components were chiral. The energies of the cycloaddition reactions are investigated through application of molecular orbital calculations at the B3LYP/6-31+G(d) theory level. A study of the different reactants' approaches and their conformational aspects revealed the stereochemical preferences of these reactions. The results of these calculations correspond well with the previously reported experimental data.
