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108273-71-8

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108273-71-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 108273-71-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,2,7 and 3 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 108273-71:
(8*1)+(7*0)+(6*8)+(5*2)+(4*7)+(3*3)+(2*7)+(1*1)=118
118 % 10 = 8
So 108273-71-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H15ClN2O3/c1-20-14(19)12(17-13(18)7-15)6-9-8-16-11-5-3-2-4-10(9)11/h2-5,8,12,16H,6-7H2,1H3,(H,17,18)

108273-71-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name METHYL 2-[(2-CHLOROACETYL)AMINO]-3-(1H-INDOL-3-YL)PROPANOATE

1.2 Other means of identification

Product number -
Other names (N-chloroacetyl)tryptophan methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:108273-71-8 SDS

108273-71-8Relevant articles and documents

Zinc complex of tryptophan appended 1,4,7,10-tetraazacyclododecane as potential anticancer agent: Synthesis and evaluation

Adhikari, Anupriya,Kumari, Neelam,Adhikari, Manish,Kumar, Nitin,Tiwari, Anjani K.,Shukla, Abha,Mishra, Anil K.,Datta, Anupama

, p. 3483 - 3490 (2017)

With the rising incidences of cancer cases, the quest for new metal based anticancer drugs has led to extensive research in cancer biology. Zinc complexes of amino acid residue side chains are well recognized for hydrolysis of phosphodiester bond in DNA a

Evaluation of methionine and tryptophan derivatised vehicles: Met-ac-TE3A / Trp-ac-TE3A for tumor imaging

Singh, Sweta,Tiwari, Anjani K.,Varshney, Raunak,Mathur, Rashi,Hazari, Puja P.,Singh,Mishra, Anil K.

, p. 41977 - 41984 (2015)

Two novel amino acid (methionine and tryptophan) appended 1,4,8,11-tetraazacyclotetradecane triacetate (TE3A) compounds Met-ac-TE3A and Trp-ac-TE3A were synthesized and evaluated for imaging applications. The pharmacokinetics of these compounds was analyzed by 99mTc labeled tracer methods. In vitro human serum stability of 99mTc labeled Met-ac-TE3A/Trp-ac-TE3A was found to be 96.5% and 96.0% after 24 h respectively. Blood kinetics of both the labeled probes on normal rabbits showed biphasic clearance. The tumor (EAT cell line) grafted in balb/c mice were readily identifiable in the gamma images. Biodistribution revealed significant tumor uptake and good contrast in the EAT tumor bearing mice and also showed high tumor/muscles ratio which is a requisite condition to work as SPECT-radiopharmaceutical for tumor imaging. To look its future applicability for therapy using M+2 and M+3 metal ions, we performed thermodynamic stability constants of complexes derived from Met-ac-TE3A and Trp-ac-TE3A with CuII and LnIII metal ions.

Compound containing indole structure as well as preparation method and application thereof

-

Paragraph 0057-0059, (2022/01/10)

According to the indole structure-containing compound and the preparation method thereof, the indole structure-containing compound has high biological activity on soil-borne pathogenic bacteria, fungi and nematodes, can be widely applied to prevention and treatment of soil-borne diseases, and provides material guarantee for safe production of crops.

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