108276-19-3Relevant academic research and scientific papers
N-Protected N-Carboxyanhydrides IX. Synthesis of N-Aralkyl α-Amino Acid N-Carboxyanhydrides by Carbonyl Insertion with Bis(N-Succinimidyl)Carbonate
Halstroem, John,Kovacs, Karoly
, p. 462 - 465 (2007/10/02)
Cyclization of N-aralkyl α-amino acids to N-carboxyanhydrides without using phosgene is reported.The weakly acidic reaction conditions allow a safe preparation od new acid-labile derivatives in peptide synthesis.
