108288-50-2

Basic information

• Product Name: (4H-BENZO[D][1,3]THIAZIN-2-YL)-O-TOLYL-AMINE
• Synonyms: N-(2-methylphenyl)-4H-3,1-benzothiazin-2-amine
• CAS NO: 108288-50-2
• Molecular Formula: C₁₅H₁₄N₂S
• Molecular Weight: 0
• Mol File: 108288-50-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 416.6°Cat760mmHg
• Flash Point: 205.7°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 3.78E-07mmHg at 25°C
• Refractive Index: 1.656
• CAS DataBase Reference: (4H-BENZO[D][1,3]THIAZIN-2-YL)-O-TOLYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (4H-BENZO[D][1,3]THIAZIN-2-YL)-O-TOLYL-AMINE(108288-50-2)
• EPA Substance Registry System: (4H-BENZO[D][1,3]THIAZIN-2-YL)-O-TOLYL-AMINE(108288-50-2)

Safety Data

• Hazardous Substances Data: 108288-50-2(Hazardous Substances Data)

Usage

General Description

(4H-Benzo[d][1,3]thiazin-2-yl)-o-tolyl-amine is a chemical compound with the molecular formula C15H12N2S. It is a heterocyclic organic compound that contains a benzothiazine ring system and a tolyl group. (4H-BENZO[D][1,3]THIAZIN-2-YL)-O-TOLYL-AMINE is commonly used in the pharmaceutical industry for the synthesis of various drugs and pharmaceuticals. It has also been studied for its potential biological activities, including its role as an antioxidant and its anticancer properties. The compound has a wide range of applications in medicinal chemistry and drug discovery due to its unique structure and potential therapeutic effects.

InChI:InChI=1/C15H14N2S/c1-11-6-2-4-8-13(11)16-15-17-14-9-5-3-7-12(14)10-18-15/h2-9H,10H2,1H3,(H,16,17)

Upstream product

• 108288-40-0 2-(bromomethyl)phenyl isothiocyanate 
• 95-53-4 o-toluidine 
• 5344-90-1 2-Aminobenzyl alcohol 
• 614-69-7 2-tolyl isothiocyanate 
• 109768-47-0 1-[2-(3-o-Tolyl-thioureido)-benzyl]-pyridinium; bromide 
• 109768-45-8 2-isothiocyanatobenzylpyridinium bromide 
• 109768-57-2 C₂₀H₁₉N₃S 

Relevant articles and documents

P(III)-Mediated Cascade C-N/C-S Bond Formation: A Protocol towards the Synthesis of N,S-Heterocycles and Spiro Compounds

A P(III)-mediated entry towards construction of C?N/C?S bond has been devised. The developed heterocyclization method was exercised for the synthesis of a diverse range of N,S-heterocycles and related spiro molecules. P(NMe2)3 revealed the maximum efficacies under the aerobic reaction conditions and a spectrum of bis-nucleophiles, and isothiocyanates were tolerated well to serve the access of manifold immense molecules. (Figure presented.).

2-ISOTHIOCYANATOBENZYLPYRIDINIUM BROMIDE - AN INTERMEDIATE FOR THE SYNTHESIS OF 2-ARYLAMINO-4H-BENZOTHIAZINES

2-Bromomethylphenyl isothiocyanate reacts with pyridine to yield 2-isothiocyanatobenzylpyridinium bromide, which afforded N-aryl-N'-(2-benzylpyridinium)thiourea bromides.Deprotonization of the latter with aqueous NaOH gave N-aryl-N'-(2-benzylpyridinium) t