108288-70-6

Upstream product

• 88841-60-5 2-Phenyl-2,3-dihydro-benzo[d]isothiazole 
• 63559-01-3 2H-benzo[b]thiete 
• 26260-02-6 2-iodobenzaldehyde 
• 76464-90-9 N-(2-iodophenylmethyl)aniline 
• 62-53-3 aniline 
• 108288-67-1 2-Phenyl-4H-3,1,2-benzoxathiazin 

Relevant academic research and scientific papers

Pd-Catalyzed Selective Synthesis of Cyclic Sulfonamides and Sulfinamides Using K2S2O5 as a Sulfur Dioxide Surrogate

A variety of cyclic sulfonamides and sulfinamides could be selectively synthesized under Pd catalysis using haloarenes bearing amino groups and a sulfur dioxide (SO2) surrogate. The amount of base was key in determining the selectivity. Mechanistic studies revealed that sulfinamides were initially formed via an unprecedented formal insertion of sulfur monoxide and were oxidized to sulfonamides in the presence of an iodide ion and DMSO.

CYCLOADDITON REACTIONS OF BENZOTHIETE AND HETERO DIENOPHILES FOR THE SYNTHESIS OF HETEROCYCLIC SYSTEMS

Benzothiete (1) undergoes cycloaddition reactions with hetero dienophiles with NN-, NO- or CO- double bonds, leading to six-membered heterocyclic ring systems of 2H-3,4-dihydro-1,2,3-benzothiadiazine (3), 4H-3,1,2-benzoxathiazine (4) and 4H-3,1-benzoxathiin.