1082948-81-9

Basic information

• Product Name: LY-2584702 (hydrochloride)
• Synonyms: LY-2584702 (hydrochloride);4-[4-[4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl]-1-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidine hydrochloride (1:1);LY2584702 HCl
• CAS NO: 1082948-81-9
• Molecular Formula: C₂₁H₁₉F₄N₇*ClH
• Molecular Weight: 481.8770128
• Mol File: 1082948-81-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: LY-2584702 (hydrochloride)(CAS DataBase Reference)
• NIST Chemistry Reference: LY-2584702 (hydrochloride)(1082948-81-9)
• EPA Substance Registry System: LY-2584702 (hydrochloride)(1082948-81-9)

Safety Data

• Hazardous Substances Data: 1082948-81-9(Hazardous Substances Data)

Usage

General Description

LY-2584702 (hydrochloride) is a potent and selective inhibitor of p38α mitogen-activated protein kinase (MAPK), which plays a key role in inflammation and cellular stress responses. It functions by targeting the ATP-binding site of the enzyme, leading to the inhibition of p38α activation and downstream signaling pathways. LY-2584702 (hydrochloride) has been shown to effectively reduce the production of pro-inflammatory cytokines and has demonstrated potential in the treatment of inflammatory diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. Additionally, it has also been studied for its potential in treating certain types of cancers and neurodegenerative diseases. Overall, LY-2584702 (hydrochloride) shows promising therapeutic potential in targeting p38α MAPK and addressing various inflammatory and stress-related conditions.

Upstream product

• 1082949-67-4 4-[4-[4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl]-1-piperidinyl]-1H-pyrazol[3,4-d]pyrimidine 

Relevant articles and documents

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