1082952-55-3

Basic information

• Product Name: N,N''-1,3-cyclohexanediylbis[N'-tricyclo[3.3.1.1(3,7)]dec-1-ylthiourea]
• CAS NO: 1082952-55-3
• Molecular Weight: 500.816
• Mol File: 1082952-55-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N''-1,3-cyclohexanediylbis[N'-tricyclo[3.3.1.1(3,7)]dec-1-ylthiourea](CAS DataBase Reference)
• NIST Chemistry Reference: N,N''-1,3-cyclohexanediylbis[N'-tricyclo[3.3.1.1(3,7)]dec-1-ylthiourea](1082952-55-3)
• EPA Substance Registry System: N,N''-1,3-cyclohexanediylbis[N'-tricyclo[3.3.1.1(3,7)]dec-1-ylthiourea](1082952-55-3)

Safety Data

• Hazardous Substances Data: 1082952-55-3(Hazardous Substances Data)

Upstream product

• 3385-21-5 1,3-diaminocyclohexane 
• 4411-26-1 1-adamantylisothiocyanate 

Relevant articles and documents

Synthesis and antiviral activities of N-Mono- and/or N,N′-Di- carbamoyl and acyl derivatives of symmetrical diamines

N-carbamoyl and N-acyl diamine derivatives were synthesized from symmetrical diamines by their addition to iso(thio)cyanates, cleavage reaction of acid anhydride, or N-acylation by acyl chloride. (1R,2R)-1,2- Diaminocyclohexane [(1R,2R)-1], meso-1,2-diaminocyclohexane (meso-1), (1R,2R)-1,2-diphenylethylenediamine [(1R,2R)-3], or meso-1,2- diphenylethylenediamine (meso-3) were used as the starting symmetrical diamines. The target compounds synthesized herein were evaluated for antiviral activity with herpes simplex virus type 1 (HSV-1). A few derivatives of 1,2-diaminocyclohexane [(1R,2R)-7aa and cis-7b] with adamantyl group(s) showed significant antiviral activity (EC50=16.0, 27.0μg/ml).