1083004-86-7Relevant academic research and scientific papers
Asymmetric synthesis of 1-tetralones bearing a remote quaternary stereocenter through rh-catalyzed cc activation of cyclopentanones
Dong, Guangbin,Ochi, Shusuke,Xia, Ying
, p. 1213 - 1217 (2020)
Herein, we describe the preparation of 1-tetralones bearing a remote quaternary stereocenter in a highly enantioselective manner. A sequence of Pd-catalyzed asymmetric 1, 4-addition and Rh-catalyzed enantiospecific CC/ CH activation delivers diverse 1-tetralones with a C4 quaternary stereocenter, which are prepared in good overall yields and high enantioselectivity.
Enantioselective synthesis of all-carbon quaternary stereogenic centers by catalytic asymmetric conjugate additions of alkyl and aryl aluminum reagents to five-, six-, and seven-membered-ring β-substituted cyclic enones
May, Tricia L.,Brown, M. Kevin,Hoveyda, Amir H.
supporting information; experimental part, p. 7358 - 7362 (2009/04/10)
(Chemical Equation Presented) Solution to pesky problems: Effective methods for catalytic asymmetric conjugate additions of alkyl and aryl aluminum reagents with unactivated β-substituted cyclopentenones are now available (see scheme). Transformations, pr
