1083055-92-8

Basic information

• Product Name: 3-chloromethyl-5-phenyl-2(5H)-furanone
• Synonyms: 3-chloromethyl-5-phenyl-2(5H)-furanone
• CAS NO: 1083055-92-8
• Molecular Weight: 208.644
• Mol File: 1083055-92-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-chloromethyl-5-phenyl-2(5H)-furanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloromethyl-5-phenyl-2(5H)-furanone(1083055-92-8)
• EPA Substance Registry System: 3-chloromethyl-5-phenyl-2(5H)-furanone(1083055-92-8)

Safety Data

• Hazardous Substances Data: 1083055-92-8(Hazardous Substances Data)

Upstream product

• 104516-09-8 1-phenylbuta-2,3-dien-1-ol 
• 201230-82-2 carbon monoxide 

Relevant articles and documents

Efficient synthesis of 3-chloromethyl-2(5H)-furanones and 3-chloromethyl- 5,6-dihydropyran-2-ones via the PdCl2-catalyzed chlorocyclocarbonylation of 2,3- or 3,4-allenols

(Chemical Equation Presented) A mild and efficient methodology involving PdCl2-catalyzed chlorocyclocarbonylation of 2,3- or 3,4-allenols with CuCl2 for the synthesis of 3-chloromethyl-2(5H)-furanones and 3-chloromethyl-5,6-dihydropyran-2-ones was developed. This reaction proceeded in a highly regioselective manner, i.e., the chlorine atom was introduced to the terminal position of the allene moiety while the lactone linkage was formed between the center carbon atom of the allene moiety and the hydroxyl oxygen, which was established by the X-ray single crystal diffraction study of γ-lactone 3p. The highly optically active 3-chloromethyl-2(5H)-furanones could be easily prepared from the readily available optically active 2,3-allenols. A mechanism for this reaction was proposed.