1083065-04-6

Basic information

• Product Name: 6H-Dibenz[b,d]azepin-6-one, 7-amino-5,7-dihydro-5-[(4-methoxyphenyl)methyl]-, hydrochloride (1:1)
• Synonyms: 6H-Dibenz[b,d]azepin-6-one, 7-amino-5,7-dihydro-5-[(4-methoxyphenyl)methyl]-, hydrochloride (1:1);7-amino-5-(4-methoxy-benzyl)-5H,7H-dibenzo[b,d]azepin-6-one hydrochloride;7-Amino-5-(4-methoxybenzyl)-5H-dibenzo[b,d]azepin-6(7H)-one hydrochloride
• CAS NO: 1083065-04-6
• Molecular Formula: C₂₂H₂₀N₂O₂*ClH
• Molecular Weight: 380.86734
• Mol File: 1083065-04-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6H-Dibenz[b,d]azepin-6-one, 7-amino-5,7-dihydro-5-[(4-methoxyphenyl)methyl]-, hydrochloride (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: 6H-Dibenz[b,d]azepin-6-one, 7-amino-5,7-dihydro-5-[(4-methoxyphenyl)methyl]-, hydrochloride (1:1)(1083065-04-6)
• EPA Substance Registry System: 6H-Dibenz[b,d]azepin-6-one, 7-amino-5,7-dihydro-5-[(4-methoxyphenyl)methyl]-, hydrochloride (1:1)(1083065-04-6)

Safety Data

• Hazardous Substances Data: 1083065-04-6(Hazardous Substances Data)

Upstream product

• 847926-87-8 5-(4-methoxybenzyl)-5H-dibenzo[b,d]azepine-6,7-dione-7-oxime 

Downstream Products

• 1083065-09-1 [(R)-5-(4-methoxy-benzyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-carbamic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 

Relevant articles and documents

Improved synthesis of (S)-7-amino-5H,7H-dibenzo[b,d]azepin-6-one, a building block for γ-secretase inhibitors

An improved synthesis of (S)-7-amino-5H,7H-dibenzo[b,d]azepin-6-one (1), involving a selective crystallization of epimeric menthylcarbamates for the resolution step followed by simultaneous cleavage of the carbamate and the lactam protecting group is desc