108309-67-7Relevant academic research and scientific papers
Synthesis and antibacterial activity of new 2-substituted penems. I
Nishi,Higashi,Takemura,Sato
, p. 1740 - 1751 (2007/10/02)
A new type of penem derivative (3 ~ 6) having a cyclic amidine moiety or a quaternary heterocycle moiety at the C-2 position was prepared. The susceptibility to renal dehydropeptidase-1 (DHP-1) and the antimicrobial activity of these compounds were determined. Some of these compounds (5,6) showed a broad spectrum of antibacterial activity, including activity against Pseudomonas aeruginosa.
