1083095-01-5Relevant academic research and scientific papers
Reduction of Δ2-isoxazolines to β-hydroxy ketones with iron and ammonium chloride as reducing agent
Jiang, Dahong,Chen, Yuanwei
supporting information; experimental part, p. 9181 - 9183 (2009/04/11)
(Chemical Equation Presented) A detailed study of a procedure for the selective reduction of Δ2-isoxazolines to the corresponding β-hydroxy ketones is reported. The use of iron and ammonium chloride as the reducing agent in the presence of water results in a facile and chemoselective protocol for the preparation of β-hydroxy ketones, including the conjugated β-hydroxy ketones.
