108321-19-3

Basic information

• Product Name: H-PRO-PNA TFA
• Synonyms: L-Proline p-nitroanilide trifluoroacetate salt prolyl aMinopeptidase substrate;(S)-N-(4-Nitrophenyl)pyrrolidine-2-carboxaMide 2,2,2-trifluoroacetate;N-(4-Nitrophenyl)pyrrolidine-2-carboxamide;P-pNA;Pro-pNA;H-L-Pro-pNA Trifluoracetate;L-PROLINE P-NITROANILIDE TRIFLUOROAC;H-Pro-pNA·TFA≥ 99% (HPLC)
• CAS NO: 108321-19-3
• Molecular Formula: C13H14F3N3O5
• Molecular Weight: 349.26
• Product Categories: Amino Acids;I - Z;Modified Amino Acids
• Mol File: 108321-19-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: H-PRO-PNA TFA(CAS DataBase Reference)
• NIST Chemistry Reference: H-PRO-PNA TFA(108321-19-3)
• EPA Substance Registry System: H-PRO-PNA TFA(108321-19-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 108321-19-3(Hazardous Substances Data)

Usage

Uses

Used in Biochemical Research:
H-PRO-PNA TFA is used as a chromogenic substrate for prolyl aminopeptidase (proline iminopeptidase) assays in biochemical research. The substrate allows for the colorimetric measurement of enzyme activity, providing a quantitative assessment of the enzyme's function and its role in peptide processing.
Used in Pharmaceutical Development:
H-PRO-PNA TFA can be utilized in the development of prolyl aminopeptidase inhibitors for potential therapeutic applications. By understanding the enzyme's activity and its interaction with H-PRO-PNA TFA, researchers can design and test compounds that modulate the enzyme's function, which may have implications in treating diseases associated with abnormal prolyl aminopeptidase activity.
Used in Diagnostic Applications:
H-PRO-PNA TFA can be employed in diagnostic assays to detect and monitor the activity of prolyl aminopeptidase in biological samples. This can be useful in identifying and tracking conditions related to the enzyme's dysregulation, providing valuable information for clinical decision-making and patient management.
Used in Quality Control:
H-PRO-PNA TFA can be used in the quality control of prolyl aminopeptidase assays and related reagents. By providing a standardized substrate, it ensures the reliability and consistency of enzyme activity measurements, which is crucial for accurate research and diagnostic applications.