1083213-30-2Relevant academic research and scientific papers
Synthesis of optically active boron-silicon bifunctional cyclopropane derivatives through enantioselective copper(I)-catalyzed reaction of allylic carbonates with a diboron derivative
Ito, Hajime,Kosaka, Yuki,Nonoyama, Kousuke,Sasaki, Yusuke,Sawamura, Masaya
supporting information; experimental part, p. 7424 - 7427 (2009/03/12)
(Chemical Equation Presented) Two for the show: A copper(I)-catalyzed reaction forms boron-silicon bifunctional cyclopropane derivatives from γ-silylated allylic carbonates and a diboron species (see scheme). The reaction is highly enantioselective when a chiral bisphosphine ligand is used. The stereoelectronic effect of the silyl group induces unusual regioselectivity of the boryl-copper(I) addition across the C-C double bond.
