1083302-75-3Relevant academic research and scientific papers
Insulin-like growth factor-1 receptor tyrosine kinase inhibitor and uses thereof
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Paragraph 0062; 0068-0070, (2020/01/25)
The invention discloses a class of compounds capable of being used as an insulin-like growth factor-1 receptor tyrosine kinase inhibitor, and a preparation method thereof, a pharmaceutical compositioncontaining the compound, and applications of the pharma
Concise stereoselective synthesis of (-)-podophyllotoxin by an intermolecular iron(III)-catalyzed Friedel-Crafts alkylation
Stadler, Daniel,Bach, Thorsten
supporting information; body text, p. 7557 - 7559 (2009/03/12)
(Chemical Equation Presented) Without further ado, the building blocks 1-3 were combined in three C-C bond-forming reactions to provide the enantiomerically pure natural product (-)-podophyllotoxin (4). The stereogenic center at C1 was generated in the key reaction, a diastereoselective iron(III)-catalyzed intermolecular Friedel-Crafts alkylation.
