1083367-49-0Relevant articles and documents
A convenient one-pot synthesis of 3,5-diarylisoxazoles via oxidative cyclisation using catalytic CuBr2 and oxone
Bhatt, Ashish,Singh, Rajesh K.,Kant, Ravi
, p. 1143 - 1147 (2019)
A facile one-pot synthesis of 3,5-diarylisoxazoles from α,β-unsaturated ketones and hydroxylamine hydrochloride is reported. The reaction is efficiently promoted by catalytic CuBr2 and Oxone to afford the desired products mostly in high yields
Green preparation method of isoxazole compound participating in water-soluble vitamin E
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Paragraph 0081-0084, (2021/11/03)
The invention provides a green synthesis method of an isoxazole compound represented by the formula (III), wherein the aldehyde oxime compound represented by the formula (I) is a substrate and is in an aqueous solution of a surfactant with a mass concentration 1 wt % - 5 wt % in N - chlorosuccinimide. The alkyne compound represented by the formula (II) is reacted 6 - 16h at room temperature under the common action of the basic substance, and the resulting reaction solution is post-treated to obtain the isoxazole compound represented by the formula (III). Water serves as a reaction solvent, the use amount of the organic solvent is reduced, and zero emission of the solvent is realized.
TBAI-catalyzed intramolecular annulation of chalcone oximes toward isoxazoles
Abdukader, Ablimit,Sun, Yadong,Zhang, Zengpeng,Liu, Chenjiang
, p. 43 - 47 (2017/11/23)
A TBAI-catalyzed intramolecular annulation of chalcone oximes toward isoxazoles was developed, providing 3,5-diarylisoxazoles in good yields. Functional groups such as methoxy, ethyoxyl, chloro, bromo, fluoro and nitro were well tolerated in this reaction