108343-90-4

Basic information

• Product Name: 2-AMINO-2-(2-METHOXYPHENYL)ETHAN-1-OL
• Synonyms: 2-AMINO-2-(2-METHOXYPHENYL)ETHAN-1-OL;b-Amino-2-methoxybenzeneethanol
• CAS NO: 108343-90-4
• Molecular Formula: C₉H₁₃NO₂
• Molecular Weight: 167.20502
• Mol File: 108343-90-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-AMINO-2-(2-METHOXYPHENYL)ETHAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-2-(2-METHOXYPHENYL)ETHAN-1-OL(108343-90-4)
• EPA Substance Registry System: 2-AMINO-2-(2-METHOXYPHENYL)ETHAN-1-OL(108343-90-4)

Safety Data

• Hazardous Substances Data: 108343-90-4(Hazardous Substances Data)

Usage

Derived from

2-methoxyphenethylamine

Functional groups

amino group, methoxy group, hydroxyl group

Classification

aromatic amine, alcohol

Physical state

white crystalline solid
Potential pharmacological properties
Potential pharmaceutical ingredient
Potential precursor in organic synthesis
Subject to further research for specific chemical, physical, and biological properties

Upstream product

• 578-57-4 2-bromoanisole 
• 135-02-4 ortho-anisaldehyde 
• 271583-59-6 2-(benzylamino)-2-(2-methoxyphenyl)acetonitrile 
• 271583-39-2 2-(benzylamino)-2-(2-methoxyphenyl)acetamide 
• 271583-23-4 2-(benzylamino)-2-(2-methoxyphenyl)acetic acid 
• 62717-78-6 2-(2-methoxyphenyl)oxirane 
• 108343-88-0 (benzyloxy)methyl 2-methoxyphenyl ketone 
• 108343-89-1 1-[1-amino-2-(phenylmethoxy)ethyl]-2-methoxy-benzene 

Downstream Products

• 1333109-72-0 N-(formyl(2-methoxyphenyl)methyl)-1-methyl-1H-indole-2-carboxamide 
• 1333109-73-1 3-(2-methoxyphenyl)-9-methyl-2H-pyrido[3,4-b]indol-1(9H)-one 
• 1333109-74-2 3-(2-hydroxyphenyl)-9-methyl-2H-pyrido[3,4-b]indol-1(9H)-one 
• 1333109-57-1 1-methyl-1H-indole-2-carboxylic acid [2-hydroxy-1-(2-methoxyphenyl)ethyl]amide 
• 869984-51-0 C₂₆H₂₆BrF₄N₃O₅ 
• 869984-48-5 C₂₈H₂₇BrF₄N₄O₅ 
• 869984-24-7 tert-butyl N-[2-hydroxy-1-(2-methoxyphenyl)ethyl]carbamate 
• 108343-94-8 [4-(2-Methoxy-phenyl)-2-oxo-oxazolidin-3-yl]-acetyl chloride 
• 108343-92-6 [4-(2-Methoxy-phenyl)-2-oxo-oxazolidin-3-yl]-acetic acid ethyl ester 
• 108343-93-7 [4-(2-Methoxy-phenyl)-2-oxo-oxazolidin-3-yl]-acetic acid 
• 108343-91-5 N-(carboxymethyl)(2-methoxyphenyl)glycinol 

Relevant articles and documents

NOVEL BENZODIOXANE-PIPERIDINE DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS FOR TREATING NEUROPSYCHIATRIC DISORDERS

The present invention concerns benzodioxane-piperidine with general formula I: wherein notably: R1 represents one or more identical or different substituent(s) on the benzene ring, each independently representing a hydrogen or halogen atom, or a C1-4 alkyl group, or a C1-4 alkoxy group or a C1-4 hydroxyalkyl group or a C1-4 alkylcarbonyl or an alkoxycarbonyl group or an OH group or an SO2R group with R alkyl, or a CN group, or a CF3 group, or an OCF 3 group; n=1, 2 or 3;m=0 or 1, andR2 represents one or more identical or different substituent(s) on the oxazolidinone or morpholinone ring, each independently representing: a hydrogen atom, a C1-4 alkyl group, or a C1-4 alkoxy group, or a C1-4 hydroxyalkyl group, or an alkylcarbonyl group, or an alkoxycarbonyl group, or an alkoxyphenyl group.

URACIL-TYPE GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATED THERETO

Compounds having utility as GnRH receptor antagonists and for treatment of a variety of sex-hormone related conditions in both men and women. Such compounds have the following structure (I): (I) wherein R1a, R1b, R1c, R2a, R2b, R3, R4, R5, R6, R7, n and X are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of structure (I) in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.