108375-66-2Relevant academic research and scientific papers
Reactions Potentially Related to Coenzyme B12 Dependent Rearrangements: Observations on the Radical -Acyl and -Thiol Ester Migrations
Best, Wayne M.,Cook, Anthony P. F.,Russell, James J.,Widdowson, David A.
, p. 1139 - 1144 (2007/10/02)
Reaction of 2-iodomethyl-2-methyl-3-oxo esters with tributyltin radicals, generated photochemically from hexabutylditin or tributyltin hydride in cyclohexane, or benzene-acetonitrile, resulted in a -acyl migration in 10-63percent yields dependent on the source of tin radical and substrate used.Radical migration was confirmed by the use of tributyltin deuteride.Thiol ester group migration was not observed.A new, highly efficient method for thiol ester synthesis is described.
