108395-21-7

Basic information

• Product Name: OCTAHYDRO-INDOLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: OCTAHYDRO-INDOLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER
• CAS NO: 108395-21-7
• Molecular Formula: C₁₃H₂₃NO₂
• Molecular Weight: 225.33
• Mol File: 108395-21-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 297.8±23.0 °C(Predicted)
• Appearance: /
• Density: 1.006±0.06 g/cm3(Predicted)
• PKA: 9.44±0.40(Predicted)
• CAS DataBase Reference: OCTAHYDRO-INDOLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: OCTAHYDRO-INDOLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER(108395-21-7)
• EPA Substance Registry System: OCTAHYDRO-INDOLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER(108395-21-7)

Safety Data

• Hazardous Substances Data: 108395-21-7(Hazardous Substances Data)

Usage

General Description

OCTAHYDRO-INDOLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER, also known as tert-butyl 1,2,3,4-tetrahydro-1H-2-benzazepine-2-carboxylate, is a chemical compound commonly used in organic synthesis. It is a tert-butyl ester derivative of octahydroindole-2-carboxylic acid, which is a key building block in the synthesis of pharmaceuticals and other organic compounds. OCTAHYDRO-INDOLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER has a wide range of applications in the pharmaceutical and chemical industries, serving as a precursor for the synthesis of various bioactive molecules. Its flexible structure and functional group compatibility make it a versatile reagent in organic chemistry. Overall, OCTAHYDRO-INDOLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER plays a crucial role in the development of new drugs and chemical products.

Upstream product

• 79799-08-9 (2S,3aS,7aS)-Octahydro-indole-2-carboxylic acid ethyl ester 
• 80828-13-3 (+/-)-(2S,3aS,7aS)-octahydroindole-2-carboxylic acid 
• 115-11-7 isobutene 
• 75-65-0 tert-butyl alcohol 
• 3770-50-1 2-carbethoxyindole 

Downstream Products

• 80828-33-7 tert-butyl (2S,3aS,7aS)-1-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)octahydro-1H-indole-2-carboxylate 
• 80828-33-7 (2S,3aS,7aS)-1-[(S)-2-((R)-1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-indole-2-carboxylic acid tert-butyl ester 
• 80876-04-6 (2R,3aR,7aR)-1-[(S)-2-((S)-1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-indole-2-carboxylic acid tert-butyl ester 
• 80828-33-7 (2R,3aR,7aR)-1-[(S)-2-((R)-1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-indole-2-carboxylic acid tert-butyl ester 
• 108449-50-9 (2S,3aS,7aS)-1-[(S)-2-((R)-1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-indole-2-carboxylic acid 
• 80923-95-1 (2R,3aR,7aR)-1-[(S)-2-((S)-1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-indole-2-carboxylic acid 
• 80828-34-8 Indolapril diacid 
• 108449-51-0 (2S,3aS,7aS)-1-[(S)-2-((R)-1-Carboxy-3-phenyl-propylamino)-propionyl]-octahydro-indole-2-carboxylic acid 
• 80876-05-7 (2R,3aR,7aR)-1-[(S)-2-((S)-1-Carboxy-3-phenyl-propylamino)-propionyl]-octahydro-indole-2-carboxylic acid 
• 108449-53-2 (2R,3aR,7aR)-1-[(S)-2-((R)-1-Carboxy-3-phenyl-propylamino)-propionyl]-octahydro-indole-2-carboxylic acid 
• 80828-32-6 Indolapril hydrochloride 
• 108449-52-1 (2R,3aR,7aR)-1-[(S)-2-((R)-1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-indole-2-carboxylic acid; hydrochloride 
• 80876-00-2 (2α,3aβ,7aβ)-octahydro-1H-indole-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

Synthesis and structure-activity relationships of potent new angiotensin converting enzyme inhibitors containing saturated bicyclic amino acids

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