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3,8-Dichloro-11H-dibenzo[c,f][1,2]diazepine, commonly known as clozapine, is a psychoactive chemical compound that belongs to the dibenzodiazepine class. It functions as a dual antagonist of serotonin and dopamine receptors, playing a crucial role in the treatment of various psychiatric conditions.

1084-98-6

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1084-98-6 Usage

Uses

Used in Pharmaceutical Industry:
Clozapine is used as an antipsychotic medication for the treatment of schizophrenia and other psychotic disorders. It is particularly effective in cases where other medications have failed to provide relief. Clozapine's unique mechanism of action, targeting both serotonin and dopamine receptors, contributes to its efficacy in managing complex psychiatric symptoms.
Used in Schizophrenia Treatment:
Clozapine is used as a second-line treatment for schizophrenia, especially in patients who have not responded well to traditional antipsychotic medications. It helps in reducing positive symptoms such as hallucinations and delusions, as well as negative symptoms like social withdrawal and emotional blunting.
Used in Suicidal Behavior Reduction:
Clozapine is used to reduce the risk of suicidal behavior in patients with schizophrenia or bipolar disorder. Its unique pharmacological profile allows it to address the underlying factors contributing to suicidal thoughts and actions, providing an additional layer of protection for these vulnerable individuals.
Used in Treatment-Resistant Schizophrenia:
Clozapine is considered a crucial medication in the management of treatment-resistant schizophrenia. Its effectiveness in this population stems from its unique receptor binding profile, which allows it to address the complex neurochemical imbalances associated with this condition.
However, it is important to note that clozapine use is associated with potentially serious side effects, such as agranulocytosis, myocarditis, and seizures. As a result, patients receiving clozapine treatment require close monitoring of blood counts and cardiac function to ensure safety and minimize risks. Despite these potential risks, clozapine remains an essential medication in psychiatric care, particularly for patients with treatment-resistant schizophrenia or those at high risk of suicidal behavior.

Check Digit Verification of cas no

The CAS Registry Mumber 1084-98-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,8 and 4 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1084-98:
(6*1)+(5*0)+(4*8)+(3*4)+(2*9)+(1*8)=76
76 % 10 = 6
So 1084-98-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H8Cl2N2/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)17-16-12(8)6-10/h1-4,6-7H,5H2

1084-98-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,8-dichloro-11H-benzo[c][1,2]benzodiazepine

1.2 Other means of identification

Product number -
Other names 3,f][1,2]diazepine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1084-98-6 SDS

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