108471-52-9Relevant academic research and scientific papers
Synthesis of novel isoxazole fused heterocycles
Rajender, P. Sarita,Sridevi,Reddy, K. Kondal
experimental part, p. 2191 - 2200 (2012/06/16)
Condensation of 3-aryl-4-formyl isoxazoles with 1,2-diamines led to the formation of 3-aryl-(6,7-benzo-1,5-heptadiazino)(3,2-d)-isoxazoles or isoxazolo-[5,4-b]-benzodiazepines and 3,10-diaryl-6,7,14,15-tetrhydro-13 H,16H-diisoxazole-(4,5-b;4,5-l)(1,4,8,11)-tetra-aza-cyclo-tetra-deca-4, 14-diones, the novel seven-and 14-membered heterocyclic systems. Similar compounds are of great importance in medicinal chemistry.
The Vilsmeier-Haack Reaction of Isoxazolin-5-ones. Synthesis and Reactivity of 2-(Dialkylamino)-1,3-oxazin-6-ones
Beccalli, Egle M.,Marchesini, Alessandro
, p. 3426 - 3434 (2007/10/02)
The Vilsmeier-Haack reaction on isoxazolin-5-ones gives 2-(dialkylamino)-1,3-oxazin-6-ones, and a reaction path is proposed depending on substitution pattern of the isoxazolin-5-ones studied.A thermal equilibrium between the oxazinones, imino ketenes, and vinyl isocyanates is hypothesized to explain most of the chemical reactivity of the 2-(dialkylamino)-1,3-oxazin-6-ones.
