108478-27-9Relevant academic research and scientific papers
Direct acylation of phenol and naphthol derivatives in a mixture of graphite and methanesulfonic acid
Sharghi, Hashem,Hosseini-Sarvari, Mona,Eskandari, Razieh
, p. 2047 - 2052 (2007/10/03)
Graphite in methanesulfonic acid is used to prepare o-hydroxyketones by direct acylation of phenol and naphthol derivatives with carboxylic acids. Georg Thieme Verlag Stuttgart.
Alumina in Methanesulfonic Acid (AMA) as a New Efficient Reagent for Direct Acylation of Phenol Derivatives and Fries Rearrangement. A Convenient Synthesis of o-Hydroxyarylketones
Sharghi, Hashem,Kaboudin, Babak
, p. 2678 - 2695 (2007/10/03)
Alumina in methanesulfonic acid (AMA) is used to prepare o-hydroxyaryl ketones by acylation of phenol and naphthol derivatives with carboxylic acids and the Fries rearrangement of phenolic esters. Mechanistic studies show that the acylation reaction in AMA occurred through an esterification followed by a Fries rearrangement of the phenolic ester by an intermolecular mechanism.
