1085192-91-1

Basic information

• Product Name: 4-Chloro-6-aminoquinoline
• Synonyms: 4-Chloro-6-aminoquinoline;4-Chloro-6-quinolinamine;4-Chloroquinolin-6-aMine
• CAS NO: 1085192-91-1
• Molecular Formula: C9H7ClN2
• Molecular Weight: 179
• EINECS: -0
• Mol File: 1085192-91-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.363
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 4-Chloro-6-aminoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-6-aminoquinoline(1085192-91-1)
• EPA Substance Registry System: 4-Chloro-6-aminoquinoline(1085192-91-1)

Safety Data

• Hazardous Substances Data: 1085192-91-1(Hazardous Substances Data)

Usage

Chemical Properties

yellow powder

Upstream product

• 101861-60-3 4-chloro-6-nitro-quinoline-1-oxide 
• 13675-92-8 6-nitroquinoline-N-oxide 
• 23432-42-0 4-hydroxy-6-nitro-quinoline 
• 611-36-9 quinolin-4-ol 
• 13675-94-0 4-chloro-6-nitroquinoline 

Relevant articles and documents

Synthesis of mono-substituted derivatives of 6-aminoquinoline

Several 6-aminoquinoline derivatives, which could be used in drug design, have been synthesized. The reaction conditions were comparatively studied, and the p-chloroaniline was used as optimum oxidant in Skraup-Doebner-Von Miller reaction. The nitro group was reduced effectively by SnCl2 with no halo-removed occurred.

AKT3 MODULATORS

Compounds of Formula la, lb, or Ic, are described, where the various substituents are defined herein. The compounds can modulate a property or effect of Akt3 in vitro or in vivo, and can also be used, individually or in combination with other agents, in the prevention or treatment of a variety of conditions. Methods for synthesizing the compounds are described. Pharmaceutical compositions and methods of using these compounds or compositions, individually or in combination with other agents or compositions, in the prevention or treatment of a variety of conditions are also described.